Longitudinal leukoxanthonychia of the thumb

Aranguren-López, Iñigo; Marquina-Iñarrairaegui, Miren; Lobo-Morán, C.; Panés-Rodríguez, A.

doi:10.1111/ijd.14345

Cited by 1 publication

(1 citation statement)

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“…We searched PubMed (https://pubmed.ncbi.nlm.nih.gov/22211430/) with the keywords “ungual SK, subungual SK, and nail SK” from September 2010 to February 2022, and found past seven cases of ungual SK, which were summarized in Table 1 4–8 including our case. The dermoscopic finding of “multiple milia‐like cysts”, which is equivalent to white round‐shaped clods in descriptive terms of dermoscopy, was observed in all cases except one without referring it.…”

Section: Discussionmentioning

confidence: 99%

Ungual seborrheic keratosis with longitudinal melanonychia: A case report

Kameda

Togawa

Maru

et al. 2022

The Journal of Dermatology

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In this paper, we report the case of a 71‐year‐old man with an 8‐year history of melanonychia on the right little finger, who referred to our hospital because the color of pigmented area had gradually darkened and the width had expanded. Physical examination revealed longitudinal melanonychia with brown color (4 mm in width). Dermoscopic examination revealed multiple white round clods and splinter hemorrhages. No micro‐Hutchinson sign was observed. We performed a punch biopsy (diameter 3 mm) of the nail matrix for diagnosis. Histopathological examination revealed irregular acanthosis of epithelium of the nail bed and distal matrix, which consisted of basaloid cells without nuclear atypia. Several zones exhibited cell whorls reminiscent of squamous eddies. The whorls were composed of large pink cells arranged in an onion peel‐like fashion. The basaloid cells tested negative for human papillomavirus in situ hybridization and p16 staining. The morphology of white round clods (milia‐like cysts in metaphoric term) observed in dermoscopic analysis corresponded to squamous eddies in histopathology. Considering these features, ungual seborrheic keratosis (SK) with longitudinal melanonychia was diagnosed, which is an atypical site for SK. We suggest that the dermoscopic finding of milia‐like cysts may be useful for the diagnosis of ungual SK.

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Section: Discussionmentioning

confidence: 99%