Longitudinal Studies of Premorbid Development of Adult Schizophrenics

Watt, Norman F.; Sáiz, C. Antón

doi:10.1016/b978-0-12-732080-9.50015-2

Cited by 8 publications

(5 citation statements)

References 117 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…In fact, even the most chronic of also has implications for the prevalence of disorders, such as schizophrenia, reflects an comorbid internalizing disorders among the episodic pattern of symptomatology with early starting antisocial group. She argued marked desistance across the life course that the adolescent-limited group engages in (Watt & Saiz, 1991). It is of great impor-certain types of delinquent offenses as a way of asserting independence and access-ing disorders across the 4-year period, from ing some adult privileges.…”

mentioning

confidence: 99%

Childhood peer rejection and aggression as predictors of stable patterns of adolescent disorder

et al. 1995

View full text Add to dashboard Cite

The significance of childhood peer rejection and aggression as predictors of adolescent disorder was tested on 1147 children who were followed longitudinally from Grade 3 through Grade 10. Growth curve analyses of parent- and self-reported problems suggested that boys who were both aggressive and rejected in third grade had profiles of increasingly severe internalizing and externalizing problems across three assessment points in adolescence. Other groups showed either decreasing symptom patterns from Grade 6 to 10 or had consistently lower problem profiles. The longitudinal patterns were more complex for the girls. Childhood peer rejection was the only predictor of stable disorder as reported by parents, whereas self-reported externalizing problems were best predicted by childhood aggression.

show abstract

mentioning

confidence: 99%

Childhood peer rejection and aggression as predictors of stable patterns of adolescent disorder

et al. 1995

View full text Add to dashboard Cite

show abstract

“…Several studies have reported the prominence of passive and withdrawn behavior in the premorbid histories of individuals with schizophrenia (Bower et al 1960; Roff et al 1976 a ; Asarnow et al 1991), particularly females (Watt 1972; Watt and Saiz 1991; Olin et al 1995). However, the results of the present analyses suggest that neither passive behavior in general nor its interaction with gender makes a substantive difference in the prediction of schizophrenia in a high-risk population.…”

Section: Discussionmentioning

confidence: 99%

A Multivariate Prediction Model of Schizophrenia

Carter

Schulsinger

Parnas

et al. 2002

Schizophrenia Bulletin

View full text Add to dashboard Cite

Univariate prediction models of schizophrenia may be adequate for hypothesis testing but are narrowly focused and limited in predictive efficacy. Therefore, we used a multivariate design to maximize the prediction of schizophrenia from premorbid measures and to evaluate the relative importance of various predictors. Two hundred twelve Danish subjects with at least one parent diagnosed in the schizophrenia spectrum (high risk) and 99 matched subjects with no such parent (low risk) were assessed on 25 premorbid variables in seven domains (genetic risk, birth factors, autonomic responsiveness, cognitive functioning, rearing environment, personality, and school behavior) when the subjects averaged 15 years of age. Twenty-five years later, 33 subjects had received lifetime diagnoses of schizophrenia. Discriminant function analyses were used to discriminate schizophrenia outcomes from no mental illness and nonschizophrenia outcomes on the basis of premorbid measures. Regardless of the comparison group used, schizophrenia was predicted by the interaction of genetic risk with rearing environment, and disruptive school behavior. Within the high-risk group, two-thirds of schizophrenia outcomes were correctly predicted by these premorbid measures; three-quarters of those with no mental illness were also correctly predicted. Prediction was enhanced among those with two schizophrenia spectrum parents, lending support to a multiplicative gene x environment model. Implications for early identification/primary prevention efforts are discussed.

show abstract

“…A number of predictors or risk factors are common antecedents of several different types of disorder. Frequently cited generic risk factors (Hawkins, Jenson, Catalano, & Lishner, 1988; Institute of Medicine, 1989; Watt & Saiz, 1991) are grouped in the Appendix into seven a priori conceptual clusters; further research may identify more basic, independent dimensions of risk underlying these clusters.…”

Section: Observations About Risk and Protective Factorsmentioning

confidence: 99%

“…Similarly, clinical outcomes should not be construed solely in dichotomous terms (e.g., recovered vs. disabled) nor as static events (e.g., addicted vs. sober) but as continuous life patterns with short-term fluctuations and long-term features. For example, almost 60% of schizophrenic patients followed for 20 or more years after the initial onset of symptoms showed recovery or significant improvement (Watt & Saiz, 1991). Thus, future prevention models should extend their sights beyond the acute onset of disorder and take account of the whole life cycle, working backward and forward from the initial clinical outcome.…”

Section: Future Directions For a National Program Of Prevention Researchmentioning

confidence: 99%

The science of prevention: A conceptual framework and some directions for a national research program.

Coie¹,

Watt²,

West³

et al. 1993

American Psychologist

Self Cite

955

691

View full text Add to dashboard Cite

A conceptual framework for studying the prevention of human dysfunction is offered. On the basis of recent advances in research on the development of psychological disorders and methods of preventive intervention, generalizations about the relation of risk and protective factors to disorder are put forward, along with a set of principles for what may be identified as the science of prevention. Emerging themes from the study of human development, in general, need to be incorporated in the models for explaining and preventing serious problems of human adaptation. The article concludes with a set of recommendations for a national prevention research agenda.

show abstract

Longitudinal Studies of Premorbid Development of Adult Schizophrenics

Cited by 8 publications

References 117 publications

Childhood peer rejection and aggression as predictors of stable patterns of adolescent disorder

Childhood peer rejection and aggression as predictors of stable patterns of adolescent disorder

A Multivariate Prediction Model of Schizophrenia

The science of prevention: A conceptual framework and some directions for a national research program.

Contact Info

Product

Resources

About