Longitudinal Study of Adaptation to the Stress of Bone Marrow Transplantation

Abstract

According to this longitudinal study, which includes pretransplant data, data from in-hospital transplantation, and posttransplant data, (1) psychosocial vulnerability of these BMT recipients was greatest during hospitalization before the transplant, (2) perceived personal control may be a potential indicator of vulnerability to secondary psychosocial morbidity, and (3) the demonstrated significance of psychosocial well-being before BMT indicates the importance of obtaining prospective data for both research and clinical purposes.

Psychosocial adjustment and quality of life among multiple myeloma patients undergoing evaluation for autologous stem cell transplantation

“…This correspondence between emotional and physical symptoms may be less evident later in the course of treatment, however, because different aspects of functioning appear to have divergent trajectories of recovery. 28,31,57 In other words, after active treatment, functional deficits may improve at a different rate than emotional distress or other psychosocial concerns (eg, fear of recurrence, financial pressures).…”

“…Continued research is needed to clarify more robust correlates or moderators of adjustment. Variables that merit further exploration based on prior theoretical and empirical work include personality resources such as optimism 58 and perceived control, 23,57 contextual factors such as supportive 23,57 and negative social interactions, 59 and coping responses such as religious activity. 60,61 Among the strengths of this investigation were use of validated measures to assess a range of outcomes among a large, homogeneous sample of myeloma patients at a similar point in treatment.…”

Adaptation of family caregivers during the acute phase of adult BMT

“…A symptomatology scale was completed by the BMT recipient at each time point as described in the discussion of procedures to provide an indicator of illness severity. 21 …”

“…This model was developed using the caregiver literature, preliminary analyses, the expertise and consultation of the BMT team, and our previous research conducted with BMT recipients. 21 Measures of these variables were selected for their validity and reliability and are described in Table 2. [21][22][23][24][25][26][27][28] The level of emotional distress was indicated by the Total Negative Affect Scale of the PANAS (Positive and Negative Affect Schedule), 22 which includes sadness, anxiety, anger and guilt.…”

A controlled randomized study examining the effects of exercise therapy on patients undergoing haematopoietic stem cell transplantation

“…All of these factors have a detrimental effect on their quality of life, as several studies have shown. [8][9][10][11] Physical exercise programmes still play only a minor role in the treatment of cancer inpatients. However, the situation during the rehabilitation phase is slightly different, as more interventions focusing on exercise can be identified, especially after breast cancer, although no studies support this trend towards an increased offer of exercise therapy.…”