“…The main neurological symptoms are gait and limb ataxia and dysarthria, accompanied by additional neurological signs, which are variable and often overlapping within the subtypes of the group. The characteristic cognitive abnormalities are executive dysfunction and visuospatial disability in the most common SCAs (SCA1, 2 and 3) [3,4]. The genetic diversity of SCAs comprises trinucleotide repeat expansions (SCA1, 2, 3, 6, 7, 8, 12, 17 and dentatorubral-pallidoluysian atrophy), pentanucleotide repeat expansions (SCA10 and 31), hexanucleotide repeat expansions (SCA36) and conventional mutations (SCA5, 11, 13, 14, 15/16, 18, 19/22, 21, 23, 26, 27, 28, 29, 34, 35, 38 and 40), whereas the responsible gene has not yet been identified in some forms of SCAs (SCA4, 20, 25, 30, 32 and 37) [5].…”