Longitudinal wall fractional shortening: an M-mode index based on mitral annular plane systolic excursion (MAPSE) that correlates and predicts left ventricular longitudinal strain (LVLS) in intensive care patients

Huang, Stephen; Ting, Iris; Huang, Andrea M.; Slama, Michel; McLean, Anthony S.

doi:10.1186/s13054-017-1876-x

Cited by 26 publications

(30 citation statements)

References 33 publications

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“…More sophisticated assessment of LV function beyond visual assessment may require training in advanced CCE. Other than mitral annular planar systolic excursion, which is a simple M-mode measurement, speckle tracking echocardiography and global longitudinal strain (GLS) are advanced measurements which may allow earlier diagnosis of septic cardiomyopathy and assist in prognostication [67][68][69]. Sanfilippo et al conducted a meta-analysis of eight studies, including 794 patients, that reported GLS and LVEF, and whilst LVEF did not show an association with mortality, worse GLS values (i.e.…”

Section: Cce For Prognostication In Septic Shockmentioning

confidence: 99%

A decade of progress in critical care echocardiography: a narrative review

et al. 2019

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Introduction: This narrative review focusing on critical care echocardiography (CCE) has been written by a group of experts in the field, with the aim of outlining the state of the art in CCE in the 10 years after its official recognition and definition. Results: In the last 10 years, CCE has become an essential branch of critical care ultrasonography and has gained general acceptance. Its use, both as a diagnostic tool and for hemodynamic monitoring, has increased markedly, influencing contemporary cardiorespiratory management. Recent studies suggest that the use of CCE may have a positive impact on outcomes. CCE may be used in critically ill patients in many different clinical situations, both in their early evaluation of in the emergency department and during intensive care unit (ICU) admission and stay. CCE has also proven its utility in perioperative settings, as well as in the management of mechanical circulatory support. CCE may be performed with very simple diagnostic objectives. This application, referred to as basic CCE, does not require a high level of training. Advanced CCE, on the other hand, uses ultrasonography for full evaluation of cardiac function and hemodynamics, and requires extensive training, with formal certification now available. Indeed, recent years have seen the creation of worldwide certification in advanced CCE. While transthoracic CCE remains the most commonly used method, the transesophageal route has gained importance, particularly for intubated and ventilated patients. Conclusion: CCE is now widely accepted by the critical care community as a valuable tool in the ICU and emergency department, and in perioperative settings.

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Section: Cce For Prognostication In Septic Shockmentioning

confidence: 99%

A decade of progress in critical care echocardiography: a narrative review

et al. 2019

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“…Such parameters have recently been shown to correlate strongly with GLS, with longitudinal wall fractional shortening being the best unbiased strain predictor. Given the simplicity of M-mode measurements, this may have significant clinical and practical implications for future critical care echocardiography investigations [ 71 ].…”

Section: Discussionmentioning

confidence: 99%

Left ventricular systolic function evaluated by strain echocardiography and relationship with mortality in patients with severe sepsis or septic shock: a systematic review and meta-analysis

et al. 2018

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BackgroundSepsis-induced myocardial dysfunction is associated with poor outcomes, but traditional measurements of systolic function such as left ventricular ejection fraction (LVEF) do not directly correlate with prognosis. Global longitudinal strain (GLS) utilizing speckle-tracking echocardiography (STE) could be a better marker of intrinsic left ventricular (LV) function, reflecting myocardial deformation rather than displacement and volume changes. We sought to investigate the prognostic value of GLS in patients with sepsis and/or septic shock.MethodsWe conducted a systematic review (PubMed and Embase up to 26 October 2017) and meta-analysis to investigate the association between GLS and mortality at longest follow up in patients with severe sepsis and/or septic shock. In the primary analysis, we included studies reporting transthoracic echocardiography data on GLS according to mortality. A secondary analysis evaluated the association between LVEF and mortality including data from studies reporting GLS.ResultsWe included eight studies in the primary analysis with a total of 794 patients (survival 68%, n = 540). We found a significant association between worse LV function and GLS values and mortality: standard mean difference (SMD) − 0.26; 95% confidence interval (CI) − 0.47, − 0.04; p = 0.02 (low heterogeneity, I2 = 43%). No significant association was found between LVEF and mortality in the same population of patients (eight studies; SMD, 0.02; 95% CI − 0.14, 0.17; p = 0.83; no heterogeneity, I2 = 3%).ConclusionsWorse GLS (less negative) values are associated with higher mortality in patients with severe sepsis or septic shock, while such association is not valid for LVEF. More critical care research is warranted to confirm the better ability of STE in demonstrating underlying intrinsic myocardial disease compared to LVEF.Electronic supplementary materialThe online version of this article (10.1186/s13054-018-2113-y) contains supplementary material, which is available to authorized users.

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“…12 TAPSE was also lower (although within normal range) in the severe group identifying early RV changes, while LVEF did not differ between groups. Huang et al 22 have recently showed that single BSA: body surface area; FEV 1 : forced expiratory volume in 1 second; lVDD: left ventricular diastolic diameter; lVSD: left ventricular systolic diameter; FS: left ventricle fractional shortening; lVEF: left ventricular ejection fraction; lA: left atria; E/A: mitral ratio of peak early to late diastolic filling velocity; RVSP: right ventricular filling pressure; TAPSE: tricuspid annular plane systolic excursion; RAP: right atrial pressure. Data are presented as mean (± SD) unless otherwise stated.…”

Section: Discussionmentioning

confidence: 99%

Subclinical Left Ventricular Dysfunction is Influenced by Genotype Severity in Patients with Cystic Fibrosis

Pallin

Keating

Kaye

et al. 2018

Clin Med Insights Circ Respir Pulm Med

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Background and objective:Over 2000 genotypes in the cystic fibrosis (CF) gene have been described. These genotypic differences result in variable clinical manifestations of CF, with severity of disease dependent on CF transmembrane conductance (CFTR) protein function. CFTR is widely distributed in nucleated cells, including cardiac myocytes, but the effect of genotype on cardiac function is not known.Methods:This retrospective review of echocardiographic data is from a single adult CF centre between 2000 and 2015. Patients were cohorted based on the functional classification of genotype. ‘Severe’ patients had both CF genes from functional classification groups 1-3; ‘mild’ patients had one or no gene from these groups, or in the event of the second gene being unknown were pancreatic sufficient.Results:Genotype and echocardiography were recorded during the inclusion period in 100 patients, 79 of whom were classified as having severe genotypes. Although the severe group were younger they had a lower fractional shortening (33.66 ± 6.6 vs 36.9 ± 6.3, P < .05), left atrial area (14.9 ± 3.6 versus 18.0 ± 4.2 cm2; P < .01) and volume (39.9 ± 18.7 versus 51.0 ± 18.7 mL; P < .05) and showed a trend to lower left ventricular ejection fraction.Conclusions:This study is the first to show that in CF, severity of genotype (functional classification) is associated with cardiac impairment. Patients with severe CF genotype and cardiac dysfunction should be identified to evaluate cardiac response to gene-modifying treatments prior to consideration for lung transplantation.

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Longitudinal wall fractional shortening: an M-mode index based on mitral annular plane systolic excursion (MAPSE) that correlates and predicts left ventricular longitudinal strain (LVLS) in intensive care patients

Cited by 26 publications

References 33 publications

A decade of progress in critical care echocardiography: a narrative review

A decade of progress in critical care echocardiography: a narrative review

Left ventricular systolic function evaluated by strain echocardiography and relationship with mortality in patients with severe sepsis or septic shock: a systematic review and meta-analysis

Subclinical Left Ventricular Dysfunction is Influenced by Genotype Severity in Patients with Cystic Fibrosis

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