Lontra longicaudis infected with canine parvovirus and parasitized by Dioctophyma renale

Abstract

This study describes a case of parvovirus infection in a river otter (Lontra longicaudis) assisted at the Wildlife Rehabilitation Center and Wildlife Screening Center, Federal University of Pelotas (UFPel), Rio Grande do Sul state, Brazil. Clinical signs included apathy, dark and fetid diarrhea, and crusted lesions on the palmar pads of the fore and hind limbs. The animal died after undergoing support treatment with antibiotics, anti-inflammatory, and fluid therapy. At necropsy, the intestines were reddened and edematous and the right kidney was diminished by one third of its normal size and covered with whitish, spongy material. A female Dioctophyma renale was found free in the abdominal cavity. Histologically, dilatation of the intestinal crypts and fusion and blunting of the intestinal villi were observed. In addition, moderate, multifocal lymphocytic enteritis with lymphoid depletion in Peyer’s patches and mesenteric lymph nodes were present. Immunohistochemistry with anti-canine parvovirus monoclonal antibody (anti-CPV) was strongly positive in the bone marrow cells and enterocytes of the intestinal crypts, confirming the diagnosis of parvovirus infection. The peritoneum on the right kidney was expanded with a cuboidal cell border, forming multiple papillary projections associated with eggs of D. renale and severe inflammatory infiltrate (giant cells, macrophages, lymphocytes, eosinophils, and plasma cells). Areas of necrosis and mineralization were also observed. Due to fragmentation and degradation of its natural habitat, the otter approached the urban area and was contaminated with the virus, which is hosted and disseminated by domestic animals. Infection with D. renale can be associated with the large population of parasitized domestic animals, which eliminate the helminth eggs through urine, contaminating the environment where the parasite intermediate and paratenic hosts co-inhabit. The diseases of these animals can be a decline factor of wild populations that inhabit the region and are an alert to spillover risk.

Occurrence of Typical Domestic Animal Viruses in Wild Carnivorans: An Emerging Threat to the Conservation of Endangered Species

“…including gastroenteric clinical signs, culminating in mortality [44,[84][85][86][87]. These same species were sampled in this study but with the occurrence of protoparvoviruses restricted only to jaguarundi, possibly reflecting the number of animals tested for each species.…”

Nefrectomia e penectomia após o diagnóstico acidental de Dioctophyme renale em cão no município de Campos do Jordão, Brasil

“…O hospedeiro definitivo se infecta alimentando-se com o fígado cru de hospedeiros intermediários contendo a L4 ou pela ingestão de água contaminada com os anelídeos (PERERA et al, 2021). Por fim, os hospedeiros definitivos são, principalmente, animais silvestres, entre eles raposas-do-campo (RIBEIRO; VEROCAI; TAVARES, 2009), lobos-guará (OLIVEIRA et al, 2021;VARZONE;AQUINO;RODOVALHO, 2008), furões (CAZATI et al, 2022;PESENTI et al, 2012;SCHWANTES et al, 2020;ZABOTT et al, 2012), lontras (ECHENIQUE et al, 2018) e quatis (MILANELO et al, 2009). Todos estes animais fazem parte da fauna silvestre da Serra da Mantiqueira (MAZZA et al, 2018;MAZZEI, 2007) e, portanto, circulam nas áreas rurais e liberam ovos de D.renale, que atingem os rios e lagos da região.…”

Outbreak of canine parvovirus 2b and Clostridium difficile infection in Asian small-clawed otters

“…Canine parvovirus 2 (CPV-2; family Parvoviridae , genus Protoparvovirus , species Carnivore protoparvovirus 1 ) causes gastrointestinal disease in several domestic and non-domestic carnivore species; the disease is of concern for mustelids, however, clinical disease has been reported only rarely. 1,3,10 We describe an outbreak of CPV-2b combined with Clostridium difficile infection causing severe necrotizing enteritis in young and adult otters.…”

“…One neotropical river otter ( Lontra longicaudis ), considered “near-threatened” on the IUCN Red List of Threatened Species, 14 infected with CPV and incidentally parasitized by Dioctophyme renale is reported, 1 but virus isolation was not performed. The source of the viral infection in our outbreak remains undetermined, but it is suspected that other carnivores may have been the source, given that some reports suggest transmission between domestic and wild carnivores.…”