Looking Beyond the Malaria Vaccine Approval to Acceptance and Adoption in Sub-Saharan Africa

Aremu, Taiwo Opeyemi; Ajibola, Oluwafemi; Oluwole, Oluwatosin Esther; Adeyinka, Kehinde Oluwatosin; Dada, Stephen Oreoluwa; Okoro, Olihe

doi:10.3389/fitd.2022.857844

Cited by 12 publications

(8 citation statements)

References 8 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Several studies have assessed the awareness of the malaria vaccine, willingness to vaccinate, acceptance of the malaria vaccine, and other parameters in several African countries such as Nigeria [ 14 , 15 ], Tanzania [ 16 ], Ghana [ 17 ], and Ethiopia [ 18 ]. They have reported high awareness status and high prospects for pediatric immunization of malaria.…”

Section: Discussionmentioning

confidence: 99%

Awareness of the Malaria Vaccine in India

Singhal¹,

Aremu²,

Garg³

et al. 2022

Cureus

View full text Add to dashboard Cite

Background: Malaria remains a serious public health problem in India. According to the World Health Organization (WHO), as per the 2021 report, India accounts for 83% of malaria cases in Southeast Asia. Various interventions have been implemented to control malaria's burden in India. In October 2021, the WHO approved the RTS,S/AS01 (RTS,S) malaria vaccine for administration in four scheduled doses in children five months of age to reduce the burden and severity of malaria. The objectives of this study were to assess public awareness about the vaccine among residents of India and determine any associations with demographic characteristics.Methods: The study was a web-based, cross-sectional survey. The survey questionnaire was sent out electronically using Qualtrics® (Provo, UT) and remained active for 12 weeks (December 2021 to March 2022). The questionnaire was self-administered anonymously, using a link that was shared with people across India through social media platforms. A total of 2,371 respondents above 18 years of age and current residents of India participated in the study. The chi-square test was used to examine the association between awareness about the vaccine and demographic characteristics. A p-value of <0.05 was used to describe a statistically significant association.Results: Most participants (71.95%) had heard about the malaria vaccine, and 68.75% favored making it a required childhood vaccine. Similarly, 67.27% indicated that they would encourage caregivers to get their children/wards vaccinated. Age, gender, educational status, residence, and caregiver status were associated with the awareness regarding the malaria vaccine (p < 0.05). Males, participants between 18 and 24 years old, and caregivers of children aged five years or less were more likely to be aware of the vaccine. Participants with higher education and residing in urban localities had more awareness of the vaccine. Conclusion:The malaria vaccine has the potential to eradicate malaria in India, especially if included in the immunization schedule for children. However, it is critical that health policymakers target populations that are less aware of information on any intended rollout of the malaria vaccine to ensure rapid uptake toward the goal of eliminating malaria from India.

show abstract

Section: Discussionmentioning

confidence: 99%

Awareness of the Malaria Vaccine in India

Singhal¹,

Aremu²,

Garg³

et al. 2022

Cureus

View full text Add to dashboard Cite

show abstract

“…Several variables were considered explanatory variables based on an extensive literature review and previous descriptive studies. 21 , 27 , 28 , 29 , 30 , 31 , 32 , 33 , 34 The variables relevant to knowledge and acceptance of the malaria vaccine included age, gender, residence, educational status, occupation, income class, family size smoking status, comorbidity, bed net, insecticide‐treated bed net, used insecticide to control mosquitoes, housing structure, house wall, house floor, house window, awareness of malaria, having ever been tested for malaria, ever been diagnosed for malaria. Our dichotomization and cutoff values were theoretical, and a verified approach might have strengthened our findings.…”

Section: Methodsmentioning

confidence: 99%

Knowledge and acceptance of malaria vaccine among parents of under‐five children of malaria endemic areas in Bangladesh: A cross‐sectional study

Amin,

Afrin,

Bonna

et al. 2023

Health Expectations

View full text Add to dashboard Cite

BackgroundMalaria exists as an endemic in many countries including Bangladesh and the malaria vaccine is not yet available here. The study aimed to assess the level of knowledge and acceptance of the malaria vaccination among the parents of children under the age of five in Bangladesh's malaria‐endemic areas and the sociodemographic, behavioural, and household factors associated with the acceptance and knowledge of the malaria vaccine.MethodsFrom January to March 2022, a cross‐sectional study was conducted in all five malaria‐endemic districts of Bangladesh, involving 405 parents of children under the age of 5 who met the inclusion criteria. Multiple logistic regression was used to analyze the factor affecting parents' acceptance and knowledge of malaria vaccination in children under five and other variables.ResultsMajority (54%) of the respondents were mothers. Almost half (49%) of the respondents were aged between 26 and 35 years old and around 90% were from rural areas. A small portion (20%) of the participants were housewives and 46% of them completed primary education. Overall, 70% of the study participants reported that they would accept malaria vaccination independently. About one‐fourth (25%) heard about the malaria vaccine and 48% of them mentioned health professionals as the source of information. Knowledge of malaria vaccination was found associated with residence, income, and family size. Acceptance and knowledge were both associated with residence, education, occupation, income, and family size. In a multivariable analysis, housing structure, house wall, house window, knowledge of malaria, testing for malaria, and being diagnosed with malaria were all associated with knowledge of and acceptance of getting vaccinated against malaria.ConclusionsThe present study highlights the necessity of creating awareness of malaria vaccines in epidemic areas of Bangladesh. This study offers crucial data to develop a policy for a novel malaria vaccine, supporting its adoption in Bangladesh.Public ContributionThis study was based on interviews. The interviewees were recruited as public representatives from the malaria‐endemic area to assist us in building an understanding of knowledge and acceptance of the malaria vaccine among parents of under‐five children in Bangladesh.

show abstract

“…Recently, the World Health Organization (WHO) has recommended that the malaria vaccine RTS, S/AS01 (RTS, S) be extensively administered to children in sub-Saharan Africa and other countries where Plasmodium falciparum, the most fatal of malaria parasites, is endemic. This advice was based on the findings of 11 pilot studies in sub-Saharan Africa, with varying levels of endemicity [87,88].…”

Section: The Clinical Management Of Malariamentioning

confidence: 99%

Malaria and HIV Co-Infection among Pregnant Women in Africa: Prevalence, Effect on Immunity and Clinical Management: Review

Obase

Bigoga

Nsagha

2023

IJTM

View full text Add to dashboard Cite

Malaria and HIV are geographically in the tropics and subtropics of the world, including sub-Saharan Africa. Understanding the overlapping effect of both infections, especially among pregnant women, is crucial in managing pregnant women during antenatal care visits, and postpartum babies. It was realized that the prevalence of malaria among HIV-positive pregnant women ranges between 31–61%, while for non-HIV infected pregnant women the prevalence still stands between 10 and 36%. Co-infection is between 0.52 and 56.3%. Even though the rate of mother-to-child transmission of HIV has dropped, MTCT of malaria still remains a problem. MTCT is associated with low birth-weight, anemia, and even immune dysregulation. The adoption of the Option B+ plan has proven to be effective in the fight against the MTCT of HIV. However, malaria in pregnancy still remains a problem. Concurrent administration of both antimalarial drugs and Cotrimozaxole to pregnant women is not recommended, because of the toxic effect of the interaction of both drugs. Nevertheless, studies looking at the effect of the current ART regimens on mothers and their children need to be carried out. Studies looking at exposed children over a longer period of time, to determine their susceptibility to malaria infection and also to monitor their immune response to malaria over time, are needed.

show abstract

Looking Beyond the Malaria Vaccine Approval to Acceptance and Adoption in Sub-Saharan Africa

Cited by 12 publications

References 8 publications

Awareness of the Malaria Vaccine in India

Awareness of the Malaria Vaccine in India

Knowledge and acceptance of malaria vaccine among parents of under‐five children of malaria endemic areas in Bangladesh: A cross‐sectional study

Malaria and HIV Co-Infection among Pregnant Women in Africa: Prevalence, Effect on Immunity and Clinical Management: Review

Contact Info

Product

Resources

About