Looking for Coronary Disease in Patients With Atrial Fibrillation

Kohli, Payal; Waters, David D.

doi:10.1016/j.cjca.2014.06.001

Cited by 7 publications

(3 citation statements)

References 18 publications

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“…However, up to 90 % of patients with CAD suffer from frequent ventricular ectopic beats [ 8 ], and/or other arrhythmias [ 9 , 10 ]. Unfortunately, the diagnostic performance of adenosine stress CMR in this important subgroup is widely unknown, since most CMR studies currently available exclude arrhythmic patients from analysis [ 6 , 11 – 13 ] fearing gating problems, or other artifacts will impair image quality [ 14 ].…”

Section: Introductionmentioning

confidence: 99%

Impact of arrhythmia on diagnostic performance of adenosine stress CMR in patients with suspected or known coronary artery disease

Greulich

Steubing

Birkmeier

et al. 2015

Journal of Cardiovascular Magnetic Resonance

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BackgroundThe diagnostic performance of adenosine stress cardiovascular magnetic resonance (CMR) in patients with arrhythmias presenting for work-up of suspected or known CAD is largely unknown, since most CMR studies currently available exclude arrhythmic patients from analysis fearing gating problems, or other artifacts will impair image quality. The primary aim of our study was to evaluate the diagnostic performance of adenosine stress CMR for detection of significant coronary stenosis in patients with arrhythmia presenting for 1) work-up of suspected coronary artery disease (CAD), or 2) work-up of ischemia in known CAD.MethodsPatients with arrhythmia referred for work-up of suspected CAD or work-up of ischemia in known CAD undergoing adenosine stress CMR were included if they had coronary angiography within four weeks of CMR.ResultsOne hundred fifty-nine patients were included (n = 64 atrial fibrillation, n = 87 frequent ventricular extrasystoles, n = 8 frequent supraventricular extrasystoles). Of these, n = 72 had suspected CAD, and n = 87 had known CAD. Diagnostic accuracy of the adenosine stress CMR for detection of significant CAD was 73 % for the entire population (sensitivity 72 %, specificity 76 %). Diagnostic accuracy was 75 % (sensitivity 80 %, specificity 74 %) in patients with suspected CAD, and 74 % (sensitivity 71 %, specificity 79 %) in the group with known CAD. For different types of arrhythmia, diagnostic accuracy of CMR was 70 % in the atrial fibrillation group, and 79 % in patients with ventricular extrasystoles. On a per coronary territory analysis, diagnostic accuracy of CMR was 77 % for stenosis of the left and 82 % for stenosis of the right coronary artery.ConclusionThe present data demonstrates good diagnostic performance of adenosine stress CMR for detection of significant coronary stenosis in patients with arrhythmia presenting for work-up of suspected CAD, or work-up of ischemia in known CAD. This holds true for a per patient, as well as for a per coronary territory analysis.

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Section: Introductionmentioning

confidence: 99%

Impact of arrhythmia on diagnostic performance of adenosine stress CMR in patients with suspected or known coronary artery disease

Greulich

Steubing

Birkmeier

et al. 2015

Journal of Cardiovascular Magnetic Resonance

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“…In fact, it is common in the elderly to find inconclusive coronary CT scans due to extensive coronary calcifications. We performed an exercise myocardial perfusion nuclear scan, showing a moderate reversible perfusion deficit at the level of the inferior wall 1 …”

Section: In Your Normal Clinical Practice Which Test Would You Do Atmentioning

confidence: 99%

Angina due to obstructive coronary artery disease with atrial fibrillation

Crea

2019

European Heart Journal Supplements

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“…Moguće je da bolesnici sa AF imaju ishemiju miokarda ali ne samo zbog koronarne stenoze već i zbog naglašenog simpatičkog tonusa koji uzrokuje pojačanu vazokonstrikciju 10,27 . Osim toga, dokazano je da postoje i uticaji srčane ishemije indukovane bolestima malih koronarnih arterija nezavisno od koronarnih stenoza velikih sudova 20 .…”

Section: Diskusijaunclassified

The incidence of atrial fibrillation in patients with coronary artery disease

Miljković¹

2018

Srce i krvni sudovi

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Uvod: Atrijalna fibrilacija(AF) je najčešća i najrasprostranjenija dugotrajna srčana aritmija kod odraslih osoba. Cilj rada je bio da se ispita učestalost AF u ambulantnih bolesnika sa angiografski potvrđenom koronarnom bolešću. Metodi: Ispitivanjem su obuhvaćena 264 bolesnika (57,5±9,4 godina) sa koronarnom bolešću, 204(77,3%) muškarca i 60(22,7%) žena. Kod svih su obavljeni klinički pregledi, stalna elektrokardiografska kontrola, laboratorijska i ehokardiografska dijagnostika i koronarografija. Rezultati: Učestalost AF u bolesnika sa koronarnom bolešću je 9,85%, paroksizmalne AF 4,17%, perzistentne i permanentne 5,68%. Nije postojala značajna razlika u učestalosti lezija jednosudovne (p>0,05), dvosudovne (p>0,05), trosudovne bolesti (p>0,05) i bolesti LM (>0,05) između bolesnika sa koronarnom bolešću, sa i bez AF. Bolesnici sa perzistentnom i permanentnom AF i koronarnom bolešću imaju značajno veću učestalost stenoza LCX (p<0,05) i RCA (p<0,01) u odnosu na one, bez AF. Nije bilo značajne razlike u učestalosti stenoza proksimalnih segmenata LCX (p>0,05) i RCA (p>0,05) između bolesnika sa koronarnom bolešću, sa i bez AF. Zaključak: Trosudovna koronarna bolest, niska ejekciona frakcija leve komore i sekundarna ishemijska bolest srca, praćena srčanom insuficijencijom, su glavni faktori koji doprinose razvoju AF u stabilnoj koronarnoj bolesti. atrijalna fibrilacija, koronarna bolest Sažetak Ključne reči Originalan rad 238 (90,2%) 20 (9,6%

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Looking for Coronary Disease in Patients With Atrial Fibrillation

Cited by 7 publications

References 18 publications

Impact of arrhythmia on diagnostic performance of adenosine stress CMR in patients with suspected or known coronary artery disease

Impact of arrhythmia on diagnostic performance of adenosine stress CMR in patients with suspected or known coronary artery disease

Angina due to obstructive coronary artery disease with atrial fibrillation

The incidence of atrial fibrillation in patients with coronary artery disease

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