Loop characteristics and audio-vestibular symptoms or hemifacial spasm: is there a correlation? A multiplanar MRI study

Stadio, Arianna Di; Dipietro, Laura; Ralli, Massimo; Faralli, Mario; Volpe, Antonio Della; Ricci, Giampietro; Messineo, Daniela

doi:10.1007/s00330-019-06309-2

Cited by 21 publications

(28 citation statements)

References 24 publications

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“…The main reason for this was said to be that the auditory fibers of the cochlear nerve have a tonotopic structure and the cochlear nerve is affected more by vascular impingement. Another point of interest in that study was that a strong correlation was reported between a decrease in the mean diameter of the cochlear nerve and tinnitus (p = 0.003) [Stadio et al, 2020].…”

Section: Discussionmentioning

confidence: 96%

“…In a recent study by Stadio et al [2020], the relationship was examined between vascular loop and facial vestibular and cochlear nerves, and it was reported that when vascular loop was present, the cochlear nerve was affected more than the other nerves. The main reason for this was said to be that the auditory fibers of the cochlear nerve have a tonotopic structure and the cochlear nerve is affected more by vascular impingement.…”

Section: Discussionmentioning

confidence: 99%

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An Evaluation of the Relationship between Retinal Nerve Fiber Thickness, Cochlear Nerve Thickness, the Level of Tinnitus, and Hearing Loss in Unilateral Tinnitus Patients

et al. 2021

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Background: In this study, optic coherence tomography (OCT) examination was performed to check whether there was any interaction between ophthalmic axonal structures in unilateral tinnitus patients, and the relationship between optic nerve thickness and cochlear nerve thickness was evaluated. Objective: The aim of the study was to evaluate the relatioship between hearing loss, tinnitus, and nerve thicknesses. Study Design: Prospective study. Setting: Tertiary referral university hospital. Patients: The study included 88 patients with unilateral tinnitus, for which no organic cause could be found in physical examination, psychiatric evaluation, or with imaging methods. Study groups were formed of the tinnitus side and control groups were formed of the healthy side as follows: Group 1 (Non-tinnitus side normal hearing values – n = 30), Group 2 (non-tinnitus side minimal hearing loss – n = 27), Group 3 (non-tinnitus side moderate hearing loss – n = 31), Group 4 (tinnitus side normal hearing values – n = 25), Group 5 (tinnitus side minimal hearing loss – n = 25), and Group 6 (tinnitus side moderate hearing loss – n = 38). Intervention: Retinal nerve fiber layer (RNFL) thickness was evaluated with OCT, and the cochlear nerve cross-sectional area was evaluated with MRI. Main Outcome Measures: RNFL measurements were taken with OCT from the subfoveal area (RNFL-SF) and 1.5 mm temporal to the fovea (RNFL-T µm) and nasal (RNFL-N µm) sectors. On MRI, 3 measurements were taken along the nerve from the cerebellopontine angle as far as the internal auditory canal, and the mean value of these 3 measurements was calculated. Results: When the groups were evaluated in respect of cochlear nerve thickness, a significant difference was seen between Group 1 and both the groups with hearing loss and the tinnitus groups. In the subgroup analysis, a statistically significant difference was determined between Group 1 and Groups 3, 4, 5, and 6 (p = 0.013, p = 0.003, p < 0.001, and p < 0.001, respectively). When the groups were evaluated in respect of the RNFL-SF (µm), RNFL-T (µm), and RNFL-N (µm) values, the differences were determined to be statistically significant (p < 0.001 for all). In the correlation analysis, a negative correlation was determined between hearing loss and cochlear nerve diameter (r: −0.184, p = 0.014), and RNFL-N (r: −0.272, p < 0.001) and between tinnitus and cochlear nerve diameter (r: −0.536, p < 0.001), and RNFL-T (r: −0.222, p < 0.009). Conclusion: The study results clearly showed a relationship between cochlear nerve fiber thickness and hearing loss and the severity of tinnitus in cases with unilateral tinnitus and that there could be neurodegenerative factors in the disease etiology. A similar relationship seen with the RNFL supports the study hypothesis.

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Section: Discussionmentioning

confidence: 96%

Section: Discussionmentioning

confidence: 99%

An Evaluation of the Relationship between Retinal Nerve Fiber Thickness, Cochlear Nerve Thickness, the Level of Tinnitus, and Hearing Loss in Unilateral Tinnitus Patients

et al. 2021

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“…In the present study, use of MPR of T2‐weighted MRI sequences facilitated detection and characterization of AC in the IAC, mirroring previous experience with this method in analysis of vascular loops of the IAC. 16 Axial views allow rapid screening for AC, measurement of cyst diameter, and localization within the IAC (PA, middle, or fundus). Sagittal slices improved detection of nerve compression.…”

Section: Discussionmentioning

confidence: 99%

“… 15 We previously reported on this approach, demonstrating utility of MPR for characterizing vascular loops features (e.g., position, contact with nerve, and vessel caliber). MPR findings have previously been correlated with auditory and vestibular symptoms 16 and discriminate benign nerve displacement from compressive nerve injury for surgical planning. 17 We hypothesized that site‐specific neural compression of cochlear or vestibular nerves in the IAC would correlate with clinical symptoms.…”

Section: Introductionmentioning

confidence: 99%

Arachnoid Cysts of the Internal Auditory Canal: Multiplanar Magnetic Resonance Imaging With Audio‐Vestibular Correlates

et al. 2021

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To investigate prevalence, radiological characteristics, and functional correlates of arachnoid cysts (AC) of the internal auditory canal (IAC) region, including associations of nerve compression with auditory/vestibular symptoms and asymmetrical audiogram or vestibular testing.Study Design: Retrospective study. Methods: T2-weighted magnetic resonance imaging (MRI) studies of IACs were retrospectively analyzed from 1247 patients with asymmetric auditory or vestibular symptoms. Patients with radiological findings of AC of the IAC were identified. Multiplanar analysis was used to analyze cyst position in the IAC and assess nerve displacement or compression. Size, position, and presence of nerve compression were correlated with symptoms.Results: Twenty-four patients had a cyst in the middle or fundus in the IAC. Diameter (P = .04) and position (P = .002) of AC were associated with symptoms. Sagittal analyses identified displacement versus compression (P = .003) more reliably than axial imaging. Symptom laterality was associated with the site of radiological abnormality. Vestibular nerve compression was associated with vertigo (P = .0001), and cochlear nerve compression was associated with auditory symptoms (P < .0001).Conclusions: In a retrospective series of patients undergoing MRI of IACs for asymmetric auditory or vestibular impairment, clinical symptom profile correlated with blinded assessment of IAC lesions.

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“…Besides that, the increase in the production of antiviral agents also happens in the lungs, being sustained by the effect of progesterone, which helps in the pulmonary repair by the release of amphiregulin. 16…”

Section: Methodsmentioning

confidence: 99%

Analysis of the Role of Female Hormones During Infection by COVID-19

Pascoal

Araujo

Lopes

et al. 2021

Rev Bras Ginecol Obstet

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Women have metabolic, immunological, and genetic variables that ensure more protection from coronavirus infection. However, the indication of treatment for several pathologies and contraception is determined by hormones that have adverse effects and raise doubts about their use during the COVID-19 pandemic. Therefore, the present study searches women specificities and the relation between female sexual hormones and COVID-19, and reports the main recommendations in this background. To this end, a review of the literature was conducted in the main databases, auxiliary data sources, and official websites. Therefore, considering the hypercoagulability status of COVID-19, the debate about the use of contraceptives due to the relative risk of thromboembolic effects that they impose arises. However, the current available evidence, as well as the recommendations of main health organs around the world, demonstrate that the use of hormonal contraceptives must be maintained during the pandemic.

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Loop characteristics and audio-vestibular symptoms or hemifacial spasm: is there a correlation? A multiplanar MRI study

Cited by 21 publications

References 24 publications

An Evaluation of the Relationship between Retinal Nerve Fiber Thickness, Cochlear Nerve Thickness, the Level of Tinnitus, and Hearing Loss in Unilateral Tinnitus Patients

An Evaluation of the Relationship between Retinal Nerve Fiber Thickness, Cochlear Nerve Thickness, the Level of Tinnitus, and Hearing Loss in Unilateral Tinnitus Patients

Arachnoid Cysts of the Internal Auditory Canal: Multiplanar Magnetic Resonance Imaging With Audio‐Vestibular Correlates

Analysis of the Role of Female Hormones During Infection by COVID-19

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