1990
DOI: 10.1136/bmj.300.6741.1690
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Loop diathermy excision of the cervical transformation zone in patients with abnormal cervical smears.

Abstract: Objective-To determine the efficacy and morbidity of fine loop diathermy excision of the cervical transformation zone as applied to the management of outpatients with abnormal cervical smears. Design-Prospective programme trial with six month follow up. Setting-Two hospital based colposcopy clinics. Patients-616 Patients aged 16-60 with abnormal cervical smears. Interventions-After colposcopic and cytological assessment excision of the cervical transformation zone by fine loop diathermy under local anaesthesia… Show more

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Cited by 193 publications
(60 citation statements)
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“…However, one of its disadvantages is potential unnecessary treatments as claimed by other authors. 1,2,3,5,11 The traditional approach with a targeted biopsy for diagnostic confirmation requires more medical visits before the actual treatment of the lesions. 11 This causes increased anxiety to patients, which can in turn lead to dropout before treatment.…”
Section: Resultsmentioning
confidence: 99%
“…However, one of its disadvantages is potential unnecessary treatments as claimed by other authors. 1,2,3,5,11 The traditional approach with a targeted biopsy for diagnostic confirmation requires more medical visits before the actual treatment of the lesions. 11 This causes increased anxiety to patients, which can in turn lead to dropout before treatment.…”
Section: Resultsmentioning
confidence: 99%
“…Here, 2.5% of the margins were damaged by artifacts, which is similar to the proportion found by other authors. 14,25,26 The literature presents many references to compromised margins, with percentages ranging from 0.0% to 30.5%, due to artifacts or fragmentation, thereby adversely affecting the histopathological interpretation. The highest rate (30.5%) was observed by Mathevet et al 27 in a study in which the equipment was not effective, and the physicians had various levels of experience with the procedure.…”
Section: Discussionmentioning
confidence: 99%
“…Several authors have expressed concern at the over-treatment rates obtained (as high as 49 %) when this practice is applied (Luesley et al 1990;Brady et al 1994). There is a significant morbidity, over and above that of simple colposcopy, such that women have every reason to be anxious about the introduction of this policy.…”
Section: Sirmentioning
confidence: 99%