Anisotropy in the speed of light that has been constrained by Michelson-Morley-type experiments also generates anisotropy in the Coulomb interactions. This anisotropy can manifest itself as an energy anisotropy in nuclear and atomic experiments. Here the experimental limits on Lorentz violation in 21 10 Ne are used to improve the limits on Lorentz symmetry violations in the photon sector, namely the anisotropy of the speed of light and the Coulomb interactions, by 7 orders of magnitude in comparison with previous experiments: the speed of light is isotropic to a part in 10 −28 .A special role in the foundation of the theory of relativity was played by the Michelson-Morley experiment searching for the anisotropy in the speed of light. Recent experiments found that the speed of light is isotropic at a level of 10 −17 − 10 −21 [1][2][3][4][5]. In Ref.[6] it was noted that this limit may be improved to the level of about 10 −29 using the NMR-type experiment [7]. Similar anisotropy in the maximal attainable speed for massive particles has been constrained for nucleons by NMR experiments ( see e.g. [7][8][9][10][11]) and for electrons using optical atomic transitions [4,5]. Observation of these or other effects of the Local Lorentz Invariance Violation (LLIV) may pave the way to a new, more general theory (see e.g. [12][13][14][15][16][17][18][19][20]).Violations of Lorentz symmetry in the photon sector are parametrized in the Standard Model Extension (SME) [20] by the tensor (k F )αβµν . In the presence of Lorentz violation, the Coulomb potential of a point charge becomes anisotropic [13] :whereare the tensor components characterizing the anisotropy in the Coulomb potential and n i = x i /r are the unit vectors along the radiusvector in the reference frame in which the components of the k F tensor are written.A nucleus that has a finite electric quadrupole moment in the absence of LLIV will exhibit a spatial energy anisotropy due to LLIV caused by the electrostatic interactions of the valence protons with the anisotropic Coulomb potential of the nuclear core. The shift of the electrostatic energy due to the LLIV correction in Eq. (1) can be written aswhere M ij is the nuclear tensor which we calculate here. Below we establish a proportionality relation between M ij and the experimental value of the nuclear electric quadrupole moment tensor Q, namely M ij = KQ ij . An estimate of the coefficient K allows us to provide estimates of the LLIV shifts for all nuclei and extract the limits on LLIV constants from corresponding experiments. We start from a simple analytical estimate of the proportionality coefficient K. To obtain the LLIV correction to the electrostatic potential of a finite size charge distribution one has to integrate Eq. (1) with a charge density distribution, and the result will not be a simple product of the unperturbed nuclear electrostatic potential Φ 0 (r) and the LLIV factor (1 + (κ DE ) ij n i n j /2). However, to clarify the dependence on the parameters of the problem it is instructive to start fro...