Lornoxicam in extracorporeal shock-wave lithotripsy; Comparison with tenoxicam and placebo in terms of analgesic consumption

Bilir, Ayten; Güleç, Sacit; Turğut, Mehmet; Cetinkaya, Dilek; Erkan, Ayse; Kurt, İmran

doi:10.1080/00365590701225988

Cited by 14 publications

(8 citation statements)

References 9 publications

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“…A single dose of 8 mg lornoxicam has proved to be effective for pain relief during SWL, being superior 20 mg of tenoxicam, which is another drug of the same class [44, 57]. …”

Section: Contemporary Drugs: Characteristics and Side Effectsmentioning

confidence: 99%

Drugs for Pain Management in Shock Wave Lithotripsy

Bach

Zaman

Kachrilas

et al. 2011

Pain Research and Treatment

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Objective. With this review, we provide a comprehensive overview of the main aspects and currently used drugs for analgesia in shockwave lithotripsy. Evidence Acquisition. We reviewed current literature, concentrating on newer articles and high-quality reviews in international journals. Results. No standardized protocols for pain control in SWL exist, although it is crucial for treatment outcome. General and spinal anaesthesia show excellent pain control but are only recommended for selected cases. The newer opioids and nonsteroidal anti-inflammatory drugs are able to deliver good analgesia. Interest in inhalation anaesthesia with nitrous oxide, local anaesthesia with deep infiltration of the tissue, and dermal anaesthesia with EMLA or DMSO has recently rekindled, showing good results in terms of pain control and a favourable side effect profile. Tamsulosin and paracetamol are further well-known drugs being currently investigated. Conclusion. Apart from classically used drugs like opioids and NSARs, medicaments like nitrous oxide, paracetamol, DMSA, or refined administration techniques for infiltration anaesthesia show a good effectiveness in pain control for SWL.

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“…A single dose of 8 mg lornoxicam has proved to be effective for pain relief during SWL, being superior 20 mg of tenoxicam, which is another drug of the same class [44, 57]. …”

Section: Contemporary Drugs: Characteristics and Side Effectsmentioning

confidence: 99%

Drugs for Pain Management in Shock Wave Lithotripsy

Bach

Zaman

Kachrilas

et al. 2011

Pain Research and Treatment

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“…(2007) reported that lornoxicam significantly reduced morphine use in patients after laparoscopic cholecystectomy compared with tenoxicam. Bilir et al. (2008) showed that lornoxicam was associated with greater pain relief than tenoxicam in patients who underwent extracorporeal shock‐wave lithotripsy.…”

Section: Discussionmentioning

confidence: 99%

The effect of analgesic education on pain in patients undergoing breast surgery: within 24 hours after the operation

Aksoy

2012

Journal of Clinical Nursing

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“…Anesthesiologists and surgeons are increasingly turning to non-opioid analgesic techniques as adjuvants for managing pain during the postoperative period. NSAIDs provide effective analgesia in patients with acute pain, either as a substitute for or as an adjunct to opioids (6). Moreover, NSAID agents deliver both central and peripheral analgesic effects in addition to their anti-inflammatory actions, and these drugs also have pre-emptive analgesic effects and are better tolerated than opioids (7).…”

Section: Discussionmentioning

confidence: 99%

Evaluation of the Analgesic Efficacy of Dexketoprofen Added to Paracetamol

Ceyhan¹,

Bilir²,

Güleç³

2017

Turk J Anaesth Reanim

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Amaç: Multimodal analjezi postoperatif ağrının tedavisinde tercih edilen bir metodtur, analjezik ilaçların aditif etkisi yan etkilerden kaçınmaya olanak sağlar. Bu çalışmada postoperatif ağrıda deksketoprofen ve parasetamol kombinasyonunun etkilerinin karşılaştı-rılması amaçlandı.Yöntemler: Non-malin jinekolojik laparatomi geçirecek 96 hasta çalışmaya dahil edildi. Hastalar randomize 3 gruba ayrıldı. Grup D'ye operasyon bitiminden 15 dakika önce, postoperatif 8. ve 16. saatlerde 50 mg intravenöz deksktoprofen verildi. Grup P'ye 1 gr intravenöz parasetamol, Grup DP'ye 500 mgr parasetamol + 25 mgr deksketoprofen intravenöz olarak aynı zamanlarda verildi. Tüm hastalara postoperatif morfin infüzyonu uygulandı. Postoperatif 24. saatin sonunda total morfin tüketimi, visual analog skala, hasta memnuniyeti ve yan etkiler değerlendirildi. Bulgular:Grup DP'deki 24.saatteki vizüel analog skala diğer gruplara göre düşük bulundu, ve bu düşüklük Grup D ile karşı-laştırıldığında istatiksel yönden anlamlı idi. Her 3 grup arasında morfin tüketimi açısından fark bulunmadı. En az sayıda yan etki Grup DP idi.Sonuç: Jinekolojik abdominal cerrahide deksketoprofen ve parasetamol birlikteliğinin morfinle kullanımı iyi analjezi ve daha az yan etki sağlamaktadır.Anahtar Kelimeler: Postoperatif ağrı, deksketoprofen, parasetamol, multimodal analjezi Objective: Multimodal analgesic methods are preferred for the treatment of postoperative pain; as a result, the additive effects of analgesics are provided while probable side effects are avoided. The current study aimed to compare the effects of the combination of dexketoprofen and paracetamol with regard to postoperative pain therapy. Methods:Ninety-six patients who underwent non-malignant gynaecological laparotomy operations were included in this study. Patients were randomized into 3 groups. Group D received 50 mg intravenous dexketoprofen 15 minutes before the end of the operation and 8 and 16 hours after the operation. Group P received 1 g intravenous paracetamol and Group DP received the combination of 500 mg paracetamol and 25 mg dexketoprofen at the same time intervals. All patients received morphine infusion after operation. Total morphine consumption at 24 hours, visual analog scale, patient satisfaction and side effects were investigated. Results:Comparison of the visual analog scale scores revealed that the Group DP presented lower scores at 24th hours compared to the other groups; and the difference between Group DP and Group D was statistically significant. Total morphine consumption was not significantly different between the three groups. The minimum number of side effects was observed in the Group DP. Conclusion:Co-administration of paracetamol, dexketoprofen and morphine provided good analgesia and fewer side effects in gynaecological abdominal surgery.

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Lornoxicam in extracorporeal shock-wave lithotripsy; Comparison with tenoxicam and placebo in terms of analgesic consumption

Abstract: In patients undergoing ESWL the i.v. administration of a single dose of 8 mg lornoxicam provides significantly better pain control compared with tenoxicam 20 mg and placebo, without increasing adverse side-effects.

Cited by 14 publications

References 9 publications

Drugs for Pain Management in Shock Wave Lithotripsy

Drugs for Pain Management in Shock Wave Lithotripsy

The effect of analgesic education on pain in patients undergoing breast surgery: within 24 hours after the operation

Evaluation of the Analgesic Efficacy of Dexketoprofen Added to Paracetamol

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