The Environmental Evaluation and Management of Dredged Material for Beneficial Use: A Regional Beneficial Use Testing Manual for the Great Lakes (a.k.a. Great Lakes Beneficial Use Testing Manual) is a resource document providing technical guidance for evaluating the suitability of dredged sediment for beneficial use in aquatic and terrestrial environments in the Great Lakes region. The procedures in this manual are based on the Environmental Laboratory extensive research, working with US Army Corps of Engineers (USACE) Great Lakes districts, state resource agencies, and local stakeholders seeking to develop dredged material beneficial use alternatives consistent with regional needs and goals. This manual is the first guidance document developed by USACE for evaluating the environmental suitability of dredged material specifically for beneficial use placements. It provides a tiered framework for evaluating the environmental suitability of aquatic and upland beneficial uses consistent with the Inland Testing Manual and the Upland Testing Manual. This manual is intended to serve as a regional platform to increase collaborative problem-solving and endorse a common understanding of the scientific and institutional practices for evaluating dredged material for any beneficial use. Dredged sediment may be managed as a valuable resource, with great potential to create economic, environmental, and social benefits.