2016
DOI: 10.1007/s10592-016-0897-3
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Loss of allelic diversity in the MHC class II DQB gene in western populations of the Japanese black bear Ursus thibetanus japonicus

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Cited by 6 publications
(4 citation statements)
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“…High genetic diversity is widely regarded as a crucial aspect of a healthy and resilient population (Rivers, Brummitt, Nic Lughadha, & Meagher, ). A rapid reduction in population size and loss of allelic diversity and heterozygosity is a feature of many populations of conservation concern (Ishibashi et al, ). Measuring genetic diversity is therefore a priority in many conservation contexts (IUCN, ), but whole genome sequencing is the only method that can truly provide a complete measure of individual or population genetic diversity (Ng & Kirkness, ).…”
Section: Introductionmentioning
confidence: 99%
“…High genetic diversity is widely regarded as a crucial aspect of a healthy and resilient population (Rivers, Brummitt, Nic Lughadha, & Meagher, ). A rapid reduction in population size and loss of allelic diversity and heterozygosity is a feature of many populations of conservation concern (Ishibashi et al, ). Measuring genetic diversity is therefore a priority in many conservation contexts (IUCN, ), but whole genome sequencing is the only method that can truly provide a complete measure of individual or population genetic diversity (Ng & Kirkness, ).…”
Section: Introductionmentioning
confidence: 99%
“…MHC is intimately linked with factors likely to affect individual fitness, population viability and evolutionary potential in changing environments. Thus, patterns of MHC diversity have been repeatedly used in a conservation context in populations of particular interest [1922].…”
Section: Introductionmentioning
confidence: 99%
“…Indeed, heterozygosity of the Shikoku individual is lower than that of Nishi‐Izu individual in spite of higher sequencing coverage (Table 1), implying that their genetic diversity has been decreasing due to the isolation of this population from the mainland populations. Ishibashi et al (2017) reported that the number of the MHC gene alleles has become reduced rapidly in the Shikoku population in recent decades. Conservation of the Japanese black bear, particularly the Shikoku population, is an urgent issue to avoid extinction.…”
Section: Discussionmentioning
confidence: 99%