Loss of dystrophin is common in uterine leiomyosarcoma: a potential biomarker for clinical application

Vadasz, Brian; Felicelli, Christopher; Yue, Feng; Yin, Ping; Zhang, Qing; Bulun, Serdar E.; Wei, Jian‐Jun

doi:10.1016/j.humpath.2022.12.011

Human Pathology

2023

DOI: 10.1016/j.humpath.2022.12.011

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Loss of dystrophin is common in uterine leiomyosarcoma: a potential biomarker for clinical application

Brian Vadasz¹,

Christopher Felicelli²,

Feng Yue³

et al.

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2024

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Advancement in Multi-omics approaches for Uterine Sarcoma

Wang,

Hu,

et al. 2024

Biomark Res

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Uterine sarcoma (US) is a rare malignant tumor that has various pathological types and high heterogeneity in the female reproductive system. Its subtle early symptoms, frequent recurrence, and resistance to radiation and chemotherapy make the prognosis for US patients very poor. Therefore, understanding the molecular mechanisms underlying tumorigenesis and progression is essential for an accurate diagnosis and targeted therapy to improve patient outcomes. Recent advancements in high-throughput molecular sequencing have allowed for a deeper understanding of diseases through multi-omics technologies. In this review, the latest progress and future potential of multi-omics technologies in US research is examined, and their roles in biomarker discovery and their application in the precise diagnosis and treatment of US are highlighted.

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Advancement in Multi-omics approaches for Uterine Sarcoma

Wang,

Hu,

et al. 2024

Biomark Res

View full text Add to dashboard Cite

show abstract

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Loss of dystrophin is common in uterine leiomyosarcoma: a potential biomarker for clinical application

Cited by 1 publication

References 36 publications

Advancement in Multi-omics approaches for Uterine Sarcoma

Advancement in Multi-omics approaches for Uterine Sarcoma

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