2012
DOI: 10.1016/j.dci.2011.04.009
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Loss of Hemolectin reduces the survival of Drosophila larvae after wounding

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Cited by 16 publications
(18 citation statements)
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“…We designed an assay to test larvae for their ability to stop bleeding, and differences were found between the feeding and wandering stages of third instar larvae that correlated with differences in the number of circulating hemocytes at the different stages (Chang et al, 2012). Using this assay, fewer hmlf03374 larvae survived when wounded in the feeding stage of the third larval instar (Chang et al, 2012). Still, most wounded hmlf03374 larvae survived.…”
Section: Coagulation Study In Vivomentioning
confidence: 98%
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“…We designed an assay to test larvae for their ability to stop bleeding, and differences were found between the feeding and wandering stages of third instar larvae that correlated with differences in the number of circulating hemocytes at the different stages (Chang et al, 2012). Using this assay, fewer hmlf03374 larvae survived when wounded in the feeding stage of the third larval instar (Chang et al, 2012). Still, most wounded hmlf03374 larvae survived.…”
Section: Coagulation Study In Vivomentioning
confidence: 98%
“…This suggested that while fon MB11923 had a greater effect than RNAi knockdown, the larvae still retain some residual fon coagulation function. In addition, we compared wildtype larvae in the feeding and wandering stages and demonstrated that like wound survival (Chang et al, 2012), hemolymph from different stage larvae showed different strand lengths. Significant differences were found between each group (P < 0.05 by t test) indicated by asterisks, while the difference between fon MB11923 and fon MB11923 /Df was highly significant (P < 0.01) as indicated by double asterisks.…”
Section: Fon Rescue: Fond 17a and Fond 27amentioning
confidence: 99%
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