Loss of motor unit size and quadriceps strength over 10years in post-polio syndrome

Quantitative muscle ultrasound and quadriceps strength in patients with post‐polio syndrome

“…The study cohort has been described in detail elsewhere . The cohort consisted of 48 adults with PPS and 12 healthy controls in the same age range who had completed strength measurements as part of a longitudinal study and agreed to participate in an additional 1‐time muscle ultrasound measurement at follow‐up in 2010.…”

“…Peak knee extension strength (in Nm) was defined as the strongest of 3 isometric maximal voluntary contractions performed on a hard‐surfaced, fixed‐chair dynamometer with knee and hip flexed at 90°. The lower leg was strapped to a lever arm containing force transducers, and visual feedback was provided by displaying the attained force on a screen …”

Relationship of depression and medications on incidence of falls among people with late effects of polio

“…Although the etiology of PPS is unknown, most electrodiagnostic examinations indicate ongoing denervation. This may be due to the effects of aging with increased metabolic demand on the enlarged motor units, overuse causing nerve cell attrition faster than reinnervation can ensue, and immunological and inflammatory occurrences (Bickerstaffe et al, 2014;Borg, 1996;Gonzalez, Olsson, and Borg, 2010;Grimby, Stalberg, Sandberg, and Sunnerhagen, 1998;Halstead, 2011).…”

Men With Late Effects of Polio Decline More Than Women in Lower Limb Muscle Strength: A 4‐Year Longitudinal Study

“…Instead, we found a significant positive linear trend for isometric ankle dorsiflexor strength measurements. Contrary to previous studies [11,20,21,23], our population consisted of roughly equal proportions of men and women (54% men). The balanced gender distribution made it possible for us to analyze if there were any differences for the men and the women in muscle strength over 4 years.…”

“…Willén et al [23] found that the decline in muscle strength over 4 years was higher in persons who were stronger at the baseline assessment. In a recent study, Bickerstaffe et al [20] showed that persons with higher isometric maximal voluntary contraction (MVC) at baseline had a greater decline in strength over 10 years.…”