Low- and high-frequency transcutaneous electrical nerve stimulation have no deleterious or teratogenic effects on pregnant mice

Neuropathic Pain due to Neurofibromatosis Treated With Transcutaneous Electrical Nerve Stimulation in a Pregnant Patient: A Case Report

“…9 By contrast, a study conducted in an animal model found that the application of low-and high-frequency TENS to the abdomen of pregnant mice caused no deleterious teratogenic effects. 10 In our case, the patient applied TENS only to the spinal column and sciatic regions. Due to anatomic differences, TENS is probably safer when applied to the spinal column rather than the abdomen due to the greater distance from the fetus.…”

Transcutaneous Electrical Nerve Stimulation (TENS) in Patients with Pregnancy-Induced Low Back Pain and/or Pelvic Girdle Pain

“…Instead, the electrodes were directly implanted in the uterus or at the nerve root of S1 [23,24]. Moreover, in a recent 3-arm placebo-controlled study, TENS was applied using frequencies of 10 Hz or 150 Hz, a pulse duration of 200 μs, and a current of 2-6 mA for the entire duration of pregnancy [25]. No complication or pathological change was observed in any maternal animal or fetus.…”

Efeitos da estimulação elétrica nervosa transcutânea na angiogênese e proliferação celular do carcinoma 4T1 de glândulas mamárias em camundongas

“…Os parâmetros utilizados para a TENS nesta pesquisa foram baseados em estudos prévios. São eles: a duração de pulso (Liebano et al, 2006;2008;Yokoyama et al, 2015), o tempo de aplicação (Sato et al, 2012;Yokoyama et al, 2015) e o período de tratamento (Sato et al, 2012;Farcic et al, 2018). O método utilizado para a intensidade aplicada se baseou no trabalho de Yokoyama et al (2012), onde a intensidade foi pré-estabelecida e foram realizados acréscimos para evitar a acomodação sensorial, a cada cinco minutos.…”