Low Basal Metabolism Following Thyrotoxicosis

Thompson, Willard O.; Thompson, Patricia J.

doi:10.1172/jci100171

Cited by 11 publications

(5 citation statements)

References 3 publications

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“…We have previously reported (16), however, that about 85 per cent of the patients with temporary low metabolism showed no clinical evidence of myxedema. Although some of these low rates without myxedema seemed to be a transient return to the patient's normal low metabolic level, there were a certain number which could be explained best by the hypothesis of a temporary hypothyroidism, not detectable clinically.…”

Section: Permanent Myxedema Following Untreated Thyrotoxicosismentioning

confidence: 88%

“…Even allowing for the deficiency in follow-up work and for the comparatively small series, the incidence of permanent myxedema is distinctly low. A temporary edema suggesting myxedema (6) is a common sequel to treatment for toxic goiter, as also is permanent low metabolism without myxedema (7). It should be kept in mind that we refer to neither of these when stressing the rarity of permanent myxedema.…”

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confidence: 99%

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Temporary and Permanent Myxedema Following Treated and Untreated Thyrotoxicosis 1

Thompson

Thompson²

1928

J. Clin. Invest.

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Although myxedema following treatment for toxic goiter has been reported frequently before, we wish to call attention to certain of its aspects which we regard as particularly worthy of emphasis, viz., (a) the existence of two types-temporary and permanent, (b) the rarity of the permanent type, (c) its late onset after x-ray therapy, (d) its occurrence following untreated toxic goiter. The permanent type will be considered first. I. PERMANENT MYXEDEMA FOLLOWING TREATED THYROTOXICOSISA. Rarity In the pioneer days of goiter surgery, when thyroidectomies were usually complete, post-operative myxedema was very common, occurring in at least 33 per cent of the cases thus treated.4 It was noted, however, that when thyroidectomies had been partial the incidence was only 1 per cent (1). The latter method soon supplanted the former, with the result that permanent myxedema became, and in general has remained, a practically negligible sequel to the surgical treatment of goiter.Judd (2)

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Section: Permanent Myxedema Following Untreated Thyrotoxicosismentioning

confidence: 88%

mentioning

confidence: 99%

Temporary and Permanent Myxedema Following Treated and Untreated Thyrotoxicosis 1

Thompson

Thompson²

1928

J. Clin. Invest.

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“…The fact that temporary low metabolism without myxedema was followed by permanent low metabolism without myxedema in one instance (case 18, fig. 6 in study II (1)). …”

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confidence: 83%

“…Accordingly, some of our temporary low rate cases without myxedema, which at present show a standard normal metabolism may eventually develop a permanent low metabolism without myxedema, as is very definitely suggested by case 18 (see fig. 6 in study II (1)). …”

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confidence: 83%