2020
DOI: 10.1055/s-0040-1705440
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Low Bleeding after Emergency CABG Using CytoSorb Adsorption of Ticagrelor: A 2-Year Clinical Experience

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“…In the past, we studied outcomes and bleeding complications after use of DOACs in patients undergoing cardiac surgery [ 15 ]. As a next step, we showed that Cytosorb ® adsorption during emergency cardiac surgery in patients at high risk of bleeding (pretreated with ticagrelor or rivaroxaban) was an effective method to reduce bleeding complications and should be used routinely in such patients [ 7 ]. This could be also verified by our group in the acute setting of aortic dissections where intraoperative hemoadsorption was capable of attenuating bleeding risk in patients pretreated with ticagrelor or rivaroxaban [ 8 ].…”
Section: Discussionmentioning
confidence: 99%
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“…In the past, we studied outcomes and bleeding complications after use of DOACs in patients undergoing cardiac surgery [ 15 ]. As a next step, we showed that Cytosorb ® adsorption during emergency cardiac surgery in patients at high risk of bleeding (pretreated with ticagrelor or rivaroxaban) was an effective method to reduce bleeding complications and should be used routinely in such patients [ 7 ]. This could be also verified by our group in the acute setting of aortic dissections where intraoperative hemoadsorption was capable of attenuating bleeding risk in patients pretreated with ticagrelor or rivaroxaban [ 8 ].…”
Section: Discussionmentioning
confidence: 99%
“…Cytosorb ® is CE marked according to the Medical Devices Directive (ISO 10,993 biocompatible, manufactured in the United States under ISO 13,485 certification). The adsorber was integrated in the CPB circuit between the oxygenator and the venous reservoir as previously described by our group [ 7 , 8 ]. Figure 1 exemplifies the intraoperative setup.…”
Section: Methodsmentioning
confidence: 99%