Low-Calorie Energy Drink Improves Physiological Response to Exercise in Previously Sedentary Men: A Placebo-Controlled Efficacy and Safety Study

Cm, Lockwood; Moon, Jordan R.; Smith, Abbie E.; Tobkin, Sarah E.; Kendall, Kristina L.; Graef, Jennifer L; Cramer, Joel T.; Stout, Jeffrey R.

doi:10.1519/jsc.0b013e3181aeb0cf

Cited by 23 publications

(25 citation statements)

References 30 publications

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“…Comparable results have been observed in other studies investigating the safety aspects of similar multi-ingredient energy/thermogenic supplements [27,28]. Following 28-days ingestion of a popular multi-ingredient thermogenic drink, Roberts and colleagues [28] reported no significant group by time interactions for lipid profiles, complete blood counts or general blood chemistry in a group of sixty college aged males.…”

Section: Discussionsupporting

confidence: 56%

“…Further, no significant effects were reported in resting cardiovascular measures (RHR, SBP and DBP). Similarly, Lockwood and colleagues [27] observed no significant changes in clinical safety markers following 10-weeks of daily supplementation with a low-calorie multi-ingredient energy drink. Both of these studies utilized supplements that contained similar amounts of caffeine (approx.…”

Section: Discussionmentioning

confidence: 99%

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Effects of 28-days ingestion of a slow-release energy supplement versus placebo on hematological and cardiovascular measures of health

Wells

Hoffman

Gonzalez

et al. 2014

Journal of the International Society of Sports Nutrition

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BackgroundRecently, slow release tablets have been developed to prolong energy release throughout the day. The efficacy of the delivery of slow-release caffeine alone is fairly well documented; however, an assessment of safety and tolerability of prolonged use of slow-release energy supplements is lacking. Therefore the objective of this study was to investigate the effect of daily ingestion of a slow-release energy supplement for 28 days on blood chemistry and resting cardiovascular measures in healthy men and women.MethodsForty healthy individuals (20 males, 20 females; age: 22.73 ± 3.06 years; height: 171.68 ± 10.45 cm; mass: 74.49 ± 15.51 kg; BMI: 25.08 ± 3.66 (kg • m2) -1) participated in this randomized, double-blind, placebo controlled study. Following a 12-hour fast, participants reported for pre-testing. Testing consisted of resting heart rate (RHR) and blood pressure (BP) measures, followed by assessment of metabolic blood chemistry, blood lipids and complete cell counts. Participants then supplemented with either Energize™ (SUPP) or placebo (PL) for 28 days. Post-testing occurred 24-hours after ingestion of the final dose and consisted of the same protocol at the same time of day as pre-testing.ResultsNo significant changes in outcome measures were observed. A significant difference between groups was observed for plasma glucose concentrations; however, follow-up testing revealed that pre- to post-supplementation changes were not significant for either SUPP or PL. All variables remained within normal adult reference ranges. No adverse events were reported.ConclusionsThese findings indicate that 28 consecutive days ingestion of a slow release energy supplement containing caffeine in caffeine users is both safe and tolerable.

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Section: Discussionsupporting

confidence: 56%

Section: Discussionmentioning

confidence: 99%

Effects of 28-days ingestion of a slow-release energy supplement versus placebo on hematological and cardiovascular measures of health

Wells

Hoffman

Gonzalez

et al. 2014

Journal of the International Society of Sports Nutrition

Self Cite

View full text Add to dashboard Cite

show abstract

Section: Discussionmentioning

confidence: 55%

“…Further, no significant effects were reported in resting cardiovascular measures (RHR, SBP and DBP). Similarly, Lockwood and colleagues [27] observed no significant changes in clinical safety markers following 10-weeks of daily supplementation with a lowcalorie multi-ingredient energy drink. Both of these studies utilized supplements that contained similar amounts of caffeine (approx.…”

Section: Discussionmentioning

confidence: 95%

Effects of 28-days ingestion of a slow-release energy supplement versus placebo on hematological and cardiovascular measures of health

Wells

Hoffman

Gonzalez

et al. 2014

J Int Soc Sports Nutr

Self Cite

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Background: Recently, slow release tablets have been developed to prolong energy release throughout the day. The efficacy of the delivery of slow-release caffeine alone is fairly well documented; however, an assessment of safety and tolerability of prolonged use of slow-release energy supplements is lacking. Therefore the objective of this study was to investigate the effect of daily ingestion of a slow-release energy supplement for 28 days on blood chemistry and resting cardiovascular measures in healthy men and women.

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“…A placebo-controlled study found that the daily use of a low-calorie energy drink paired with an exercise program resulted in improved exercise adaptations in a group of previously sedentary men (Lockwood et al, 2010). The exercise program included 3 days of cycling and 2 days of resistance training per week.…”

Section: Energy Drinks Reliably Enhance Aerobic Performancementioning

confidence: 99%

Effect of an Energy Drink on Physical and Cognitive Performance in Trained Cyclists

Lassiter

Kammer

Burns

et al. 2012

Journal of Caffeine Research

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Dedication This work is dedicated to those who have supported me outside of my graduate studies over the last few years. My family deserves as much credit as anyone for the work generated as part of this study. Namely, Kristin Bagby, Christine Lassiter, Mechelle Lassiter, Bette Rose Ryan, and Michele Poague deserve recognition; without them I would not have been able to work as tirelessly as I have on this project. v Acknowledgements Many individuals contributed significantly to the completion of this project. Though the thesis is my own, the project is a result of a team effort. First and foremost Lynne Kammer helped me every step of the research process, from study design, to data collection, and proofreading. Zhenping Ding played another critical role in training and overseeing the completion of the biochemistry techniques used as part of this work. Assays were completed is listed last, his help on this and other projects that I have been a part of is understated and I commend him for being such a hard-working and loyal individual. My graduate studies have been made possible through the concerted efforts of the entire kinesiology staff at the University of Texas and I would like to recognize the contributions to my education made by Ivy have served as readers for my thesis and for this I owe them recognition. Lastly I would like to thank the sponsor of my research, SWSS law, and the participants who were willing to ride their bikes in the lab for the sake of expanding our scientific understanding. vi Abstract Effect of an Energy Drink on Physical and Cognitive Performance in Trained Cyclists David Gray Lassiter, MS KIN The University of Texas at Austin, 2012 Supervisor: John Ivy This study investigated the effectiveness of an energy drink (ED) in enhancing cycling time-trial performance, and cognitive performance at rest, during moderate-intensity exercise, and after exercise. The protocol was double-blind, randomized, placebo-controlled, two-period, and within-subjects. The treatments were ED containing caffeine and carbohydrate, and a caffeine-free non-caloric flavored placebo beverage (PLA). Exercise performance was measured by time to finish a simulated 35 km time-trial course. Cognitive performance was measured by a Stroop task, a tapping task, a reaction time task, and an executive function task consisting of both tapping and reaction time. The effects of ED on blood markers were also assessed. Race performance was enhanced by an average of 3% when participants had ED compared to PLA without a difference in rating of perceived exertion (RPE). Performance was improved by ED even in participants that arrived to the lab with elevated blood caffeine concentrations. Both before and after the exercise, ED resulted in more taps per second in the tapping task. After receiving ED, plasma insulin spiked, there was a fall in free fatty acids (FFA) and vii blood glucose remained unchanged. Exercise onset caused a drop in blood glucose when participants consumed ED, though glucose returned to a level that was not di...

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Low-Calorie Energy Drink Improves Physiological Response to Exercise in Previously Sedentary Men: A Placebo-Controlled Efficacy and Safety Study

Cited by 23 publications

References 30 publications

Effects of 28-days ingestion of a slow-release energy supplement versus placebo on hematological and cardiovascular measures of health

Effects of 28-days ingestion of a slow-release energy supplement versus placebo on hematological and cardiovascular measures of health

Effects of 28-days ingestion of a slow-release energy supplement versus placebo on hematological and cardiovascular measures of health

Effect of an Energy Drink on Physical and Cognitive Performance in Trained Cyclists

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