Low-coherence lock-in interferometer for ophthalmology

Oliveira, A. C.; Yasuoka, Fátima M. M.; Santos, Jesulino Bispo dos; Carvalho, Luciane Bizari Coin de; Castro, Jarbas C.

doi:10.1063/1.1148867

Cited by 8 publications

(1 citation statement)

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“…[12][13]31 The resulting relative rotation of light polarization that are due to glucose in the aqueous humor can be determined simultaneously from the different chromatic channels by spectrally resolved signal detection performed by the angle detection unit. For simultaneous determination of the corresponding optical path l ah of the reflected light beam inside the aqueous humor, the application of low-coherence interferometry [32][33][34][35] is proposed at the path length detection unit.…”

Section: Working Principle Of the Novel Glucose Sensormentioning

confidence: 99%

New optical scheme for a polarimetric-based glucose sensor

Ansari

Böckle²,

Rovati

2004

J. Biomed. Opt.

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A new optical scheme to detect glucose concentration in the aqueous humor of the eye is presented. The ultimate aim is to apply this technique in designing a new instrument for, routinely and frequently, noninvasively monitoring blood glucose levels in diabetic patients without contact (no index matching) between the eye and the instrument. The optical scheme exploits the Brewster reflection of circularly polarized light off of the lens of the eye. Theoretically, this reflected linearly polarized light on its way to the detector is expected to rotate its state of polarization, owing to the presence of glucose molecules in the aqueous humor of a patient's eye. An experimental laboratory setup based on this scheme was designed and tested by measuring a range of known concentrations of glucose solutions dissolved in water. (c) 2004 Society of Photo-Optical Instrumentation Engineers.

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