In harsh battlefield environments, tanks have to encounter some nonlinear characteristics including frictional moment, gear backlash and parameter drifts, etc. The existence of such nonlinear characteristics makes the controller design of tank gun control systems (TGCSs) challenging. In this paper, a barrier neuroadaptive control approach is proposed to handle the uncertainties and nonlinearities, so as to achieve satisfactory tracking performance for TGCSs. With a time-varying barrier Lyapunov function employed in controller design, the output error of TGCS is restricted within the preset bound during the control process. A radial basis function (RBF) neural network is built to approximate the uncertainties in tank gun control systems. An anti-windup control strategy is developed to deal with the input saturation nonlinearity, with a Nussbaum function used to compensate for the nonlinear term arising from input saturation. By reasonably applying filtering error into output-constrained adaptive backstepping control design, the three steps in the traditional backstepping control design are reduced to two steps. The asymptotic stability of the closed-loop TGCSs is proven by Lyapunov theory. Finally, a simulation example is presented to verify the effectiveness of the proposed control scheme.INDEX TERMS Tank gun control systems; adaptive control; input saturation; time-varying output constraint