Low Dose Bleomycin Every Three Weeks with Cisplatin and Etoposide Results in Excellent Event Free and Survival Rates for Children and Adolescents with Gonadal Malignant Germ Cell Tumours (MGCT): a POG/CCG Intergroup Report

Cullen, John W.; Olson, T.; Giller, Roger; Lauer, Stephen J.; Cushing, Barbara; Rogers, Penelope; London, W. B.; Albin, Anna-Karin; Weetman, Robert M.

doi:10.1007/978-1-4471-3281-3_23

Cited by 2 publications

(1 citation statement)

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“…Patients with progression are treated as those with intermediate risk and given 3 cycles of compressed BEP 14. This regimen differs from the adult BEP regimen by reducing the dose of bleomycin from 15 U/m 2 weekly to 15 U/m 2 every 3 weeks, and by compressing the doses of cisplatin (total dose 100 mg/m 2 per cycle) and etoposide (total dose 500 mg/m 2 per cycle) over 3 days instead of 5 days 15.…”

Section: Clinical Managementmentioning

confidence: 99%

Testicular Cancer: A Prototypic Tumor of Young Adults

Hayes‐Lattin

Nichols

2009

Seminars in Oncology

103

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Testicular cancer is the most common solid tumor among males in the 20-39 year-old age range. Moreover, testicular cancer has unique biological associations, clinical features, and psychosocial impacts that establish this tumor as a prototypic malignancy of young adults. The biology of testicular germ cell tumors after puberty is distinctive. Epidemiologic patterns of testicular cancer suggest etiologic factors that may be congenital, racial, and geographic. The clinical management of a cancer common among young adults, but rare among adults in general, requires expertise so as not to jeopardize the high rates of survivorship associated with modern therapy. The concurrent but separate development of staging, prognostic systems and treatment recommendations, between the fields of pediatric and adult oncology, highlight the need for increased integration and cooperation across these subspecialties. And the high rate of survival, combined with the need for long term monitoring for relapse or late effects, demonstrates the challenge of delivering longitudinal care in this mobile and active young adult population.

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Section: Clinical Managementmentioning

confidence: 99%