Low-Dose CT for Lung Cancer Screening

Kalra, Mannudeep K.

doi:10.1016/j.jacr.2017.01.052

Cited by 5 publications

(9 citation statements)

References 8 publications

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“…Currently, the manufacturer recommends NI = 10 to 11 as the default value for a regular thoracic CT scan. The 5-level evaluation of the application of different NI values performed by Kalra [ 14 ] recommended NI = 12 to 15 for adult thoracic CT scans. In this study, NI = 11 was selected as the regular scan dose.…”

Section: Discussionmentioning

confidence: 99%

“…Two experienced radiology physicians with more than 15 years of experience in image diagnosis performed double-blind evaluations on the raw images obtained using different NIs and on the post-treated images using Bone Reading software to diagnose rib fractures. The 5-point scoring system employed by Kalra [ 14 ] was referenced for image evaluations. The acceptance rate of image diagnosis was evaluated using the following scale: 1 - insufficiency, where the diagnosis requirements were completely not met; 2 - below standard, where the diagnosis requirements were not met; 3 - average performance, where the diagnosis requirements were met; 4 - good performance, where the diagnosis requirements were met; and 5 - outstanding performance, where the diagnosis requirements were met.…”

Section: Methodsmentioning

confidence: 99%

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Low-dose CT examination for rib fracture evaluation

Jin

et al. 2018

Medicine

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The aim of this study was to assess the applicability of low-dose thoracic computed tomography (CT) in the diagnosis of rib fractures.A total of 37 trauma patients were selected for CT scanning using a noise index (NI) model. Each patient was scanned at both NI = 11 and NI = 26, while the other scanning parameters were kept the same. The scanning dose length product (DLP) and effective dose (ED) were recorded after each examination. Two radiologists diagnosed the rib fractures by degree (I, II, III, and IV) using Bone Reading software and axial images. Image quality was scored by 2 experienced radiologists using a 5-point scale. The numbers and degrees of rib fractures for different NIs were recorded and tested using the Chi-squared test. The interobserver differences were determined by kappa statistics.The CTDIvols and EDs for NI = 11 and NI = 26 were 9.82 ± 4.78, 5.75 ± 2.75, and 2.14 ± 1.19 and 1.24 ± 0.73, respectively; the latter was decreased by 78.2% and 78.4% relative to the former. Low-dose thoracic CT was feasible for the auxiliary diagnosis of rib fractures using Bone Reading software (P > .05). There was perfect interobserver concordance in terms of diagnostic acceptability (kappa = 0.931, 0.905).The use of an appropriate low-dose CT scanning technique is satisfactory for the assessment and diagnosis of rib fractures.

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Section: Discussionmentioning

confidence: 99%

Section: Methodsmentioning

confidence: 99%

Low-dose CT examination for rib fracture evaluation

Jin

et al. 2018

Medicine

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“…9,14 Considering the volume of CT scans performed, creating and optimizing LDCT protocols for frequently performed CT chest examinations would be beneficial in further reducing patient radiation doses, particularly in LCS. 10,15 Data were collected in Norway and Canada due to the similarities of their healthcare systems. This study aims to assess non-contrast LDCT protocols of CT scanners routinely used in clinical settings in Norway and Canada and examine the impact of the scanners and protocols on patient dose and image quality.…”

Section: Introductionmentioning

confidence: 99%

“… 5 CT provides exceptional visualization of the high-contrast structures of the lungs, making LDCT an invaluable tool in diagnosing lung pathology and the modality of choice for lung cancer screening (LCS). 10 Common indications for LDCT chest protocols include metastases, lung nodules, focal lung pathology, and evaluation and monitoring of chronic lung diseases like emphysema and cystic fibrosis. 11 In some institutions, LDCT has become the preferred protocol for routine chest examinations, rather than SDCT.…”

Section: Introductionmentioning

confidence: 99%

A multi-institutional assessment of low-dose protocols in chest computed tomography: Dose and image quality

Tonkopi,

Tetteh,

Gunn

et al. 2024

Acta Radiologica Open

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Background Low-dose CT (LDCT) chest protocols have widespread clinical applications for many indications; as a result, there is a need for protocol assessment prior to standardization. Dalhousie University and Oslo Metropolitan University have a formally established cooperative relationship. Purpose The purpose is to assess radiation dose and image quality for LDCT chest protocols in seven different hospital locations in Norway and Canada. Material and methods Retrospective dosimetry data, volumetric CT dose index (CTDIvol), and dose length product (DLP) from 240 average-sized patients as well as CT protocol parameters were included in the survey. Effective dose (ED) and size-specific dose estimate (SSDE) were calculated for each examination. For a quantitative image quality analysis, noise, CT number, and signal-to-noise ratio (SNR) were determined for three regions in the chest. The contrast-to-noise ratio (CNR) was calculated for lung parenchyma in comparison to the subcutaneous fat. Differences in dose and image quality were evaluated by a single-factor ANOVA test. A two-sample t-test was performed to determine differences in means between individual scanners. Results The ANOVA test revealed significant differences ( p < .05) in dose values for all scanners, including identical scanner models. Statistically significant differences ( p < .05) were determined in mean values of the SNR distributions between the scanners in all three measured regions in the chest, as well as the CNR values. Conclusion The observed variations in dose and image quality measurements, even within the same hospitals and between identical scanner models, indicate a potential for protocol optimization in the involved hospitals in both countries.

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“…A recommendation has been made that this application of CT should be justified for dose levels with the volume-weighted CT dose index (CTDI vol ) <3.0 mGy for standard size patients. [34] Effective dose is the parameter related to the risk from exposure to ionizing radiation. For CT, it can be calculated from multiplication of the dose length product (DLP) by a DLP to effective dose conversion factor.…”

Section: Introductionmentioning

confidence: 99%

The investigation of dose and image quality of chest computed tomography using different combinations of noise index and adaptive statistic iterative reconstruction level

Sookpeng

Martin

Butdee

2019

Indian Journal of Radiology and Imaging

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Background: Computed tomography (CT) automatic tube current modulation (ATCM) systems and iterative reconstruction (IR) play an important role in CT radiation dose optimization. How the two can best be used together is one of the challenges faced by radiology professionals. Aim: To determine optimum settings of ATCM noise index (NI) together with adaptive statistic iterative reconstruction (ASIR) for a general electric (GE) scanner that aims to achieve similar image quality to the standard protocol used in the hospital (Smart mA technique with NI of 11.57 and 30% ASIR reconstruction) with a lower dose. Methods: Different NI and ASIR levels were set for scans of a phantom. Objective image quality assessments in terms of noise, signal-to-noise ratio (SNR), contrast-to-noise ratio (CNR), low-contrast detectability (LCD), and modulation transfer function (MTF) were carried out in an anthropomorphic chest and a Catphan 700 phantom. Subjective image quality assessment was also performed with five readers to confirm whether the image quality of the new protocols was adequate. Result and Conclusion: SNR and CNR increased with the strength of ASIR, and decreased with higher NI settings. The MTF improved slightly for higher dose levels and from filtered back projection (FBP) to higher strength of ASIR. LCD improved with ASIR compared to FBP and with higher strengths of ASIR. Qualitative scoring ranged between 3.0 and 4.6. A moderate degree of reliability was found between scoring. Use of NI 15.04 with 70% ASIR can reduce dose by 41% compared to the standard protocol of NI 11.57 with 30% ASIR without degradation of image quality.

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Low-Dose CT for Lung Cancer Screening

Cited by 5 publications

References 8 publications

Low-dose CT examination for rib fracture evaluation

Low-dose CT examination for rib fracture evaluation

A multi-institutional assessment of low-dose protocols in chest computed tomography: Dose and image quality

The investigation of dose and image quality of chest computed tomography using different combinations of noise index and adaptive statistic iterative reconstruction level

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