Low-dose CT for patients with clinically suspected acute appendicitis: optimal strength of sinogram affirmed iterative reconstruction for image quality and diagnostic performance

Kim, Seung Ho; Yoon, Junghee; Lee, Jang Hee; Lim, Yun‐Jung; Kim, Ok Hwa; Ryu, Ji Hwa; Son, Jung-Hee

doi:10.1177/0284185114542297

Cited by 23 publications

(15 citation statements)

References 27 publications

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“…For IR, we applied SAFIRE level 3 because this strength level is commonly used in clinical routine. 22,23 In addition, we included SAFIRE level 5 to our analysis, despite of its known "plastic-like," blotchy image appearance. 24 By doing so, we wanted to evaluate to which extent noise can be maximally reduced.…”

Section: Discussionmentioning

confidence: 99%

Photon Counting Computed Tomography With Dedicated Sharp Convolution Kernels

et al. 2018

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Section: Discussionmentioning

confidence: 99%

Photon Counting Computed Tomography With Dedicated Sharp Convolution Kernels

et al. 2018

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“…Model-based IR with use of raw data alone can take as long as 20-30 minutes for abdominopelvic scans (35,36). Reconstruction with SAFIRE, which uses both raw and image data space, can be performed at the scanner at a rate of approximately 20 images per second; hence, SAFIRE can be easily incorporated into routine practice (37). This study was limited by its retrospective nature.…”

Section: Discussionmentioning

confidence: 99%

Diagnostic Accuracy of CT Enterography for Active Inflammatory Terminal Ileal Crohn Disease: Comparison of Full-Dose and Half-Dose Images Reconstructed with FBP and Half-Dose Images with SAFIRE

Gandhi¹,

Baker²,

Goenka³

et al. 2016

Radiology

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Purpose To compare the diagnostic accuracy and image quality of computed tomographic (CT) enterographic images obtained at half dose and reconstructed with filtered back projection (FBP) and sinogram-affirmed iterative reconstruction (SAFIRE) with those of full-dose CT enterographic images reconstructed with FBP for active inflammatory terminal or neoterminal ileal Crohn disease. Materials and Methods This retrospective study was compliant with HIPAA and approved by the institutional review board. The requirement to obtain informed consent was waived. Ninety subjects (45 with active terminal ileal Crohn disease and 45 without Crohn disease) underwent CT enterography with a dual-source CT unit. The reference standard for confirmation of active Crohn disease was active terminal ileal Crohn disease based on ileocolonoscopy or established Crohn disease and imaging features of active terminal ileal Crohn disease. Data from both tubes were reconstructed with FBP (100% exposure); data from the primary tube (50% exposure) were reconstructed with FBP and SAFIRE strengths 3 and 4, yielding four datasets per CT enterographic examination. The mean volume CT dose index (CTDIvol) and size-specific dose estimate (SSDE) at full dose were 13.1 mGy (median, 7.36 mGy) and 15.9 mGy (median, 13.06 mGy), respectively, and those at half dose were 6.55 mGy (median, 3.68 mGy) and 7.95 mGy (median, 6.5 mGy). Images were subjectively evaluated by eight radiologists for quality and diagnostic confidence for Crohn disease. Areas under the receiver operating characteristic curves (AUCs) were estimated, and the multireader, multicase analysis of variance method was used to compare reconstruction methods on the basis of a noninferiority margin of 0.05. Results The mean AUCs with half-dose scans (FBP, 0.908; SAFIRE 3, 0.935; SAFIRE 4, 0.924) were noninferior to the mean AUC with full-dose FBP scans (0.908; P < .003). The proportion of images with inferior quality was significantly higher with all half-dose reconstructions than with full-dose FBP (mean proportion: 0.117 for half-dose FBP, 0.054 for half-dose SAFIRE 3, 0.054 for half-dose SAFIRE 4, and 0.017 for full-dose FBP; P < .001). Conclusion The diagnostic accuracy of half-dose CT enterography with FBP and SAFIRE is statistically noninferior to that of full-dose CT enterography for active inflammatory terminal ileal Crohn disease, despite an inferior subjective image quality. (©) RSNA, 2016 Online supplemental material is available for this article.

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“…Therefore it might be prudent to increase the tube charge somewhat, to reduce the noise level at the cost of a slight dose increase. At a low-dose level of 1-2 mSv, appendicitis can be diagnosed with CT with the same confidence as with a standard dose of 5-7 mSv [21,22]. Abdominal radiography in our institution consists routinely of the three images mentioned above.…”

Section: Discussionmentioning

confidence: 99%

Diagnostic accuracy of low-dose CT compared with abdominal radiography in non-traumatic acute abdominal pain: prospective study and systematic review

et al. 2015

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Low-dose CT for patients with clinically suspected acute appendicitis: optimal strength of sinogram affirmed iterative reconstruction for image quality and diagnostic performance

Abstract: Although measured noise declined as SAFIRE strength increased, S3 seems optimal for the best subjective image quality on LDCT 30mAs. The diagnostic performance of LDCT 30mAs with any strength is comparable to that of LDCT 100mAs for the diagnosis of acute appendicitis.

Cited by 23 publications

References 27 publications

Photon Counting Computed Tomography With Dedicated Sharp Convolution Kernels

Photon Counting Computed Tomography With Dedicated Sharp Convolution Kernels

Diagnostic Accuracy of CT Enterography for Active Inflammatory Terminal Ileal Crohn Disease: Comparison of Full-Dose and Half-Dose Images Reconstructed with FBP and Half-Dose Images with SAFIRE

Diagnostic accuracy of low-dose CT compared with abdominal radiography in non-traumatic acute abdominal pain: prospective study and systematic review

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