Low-Dose Hormonal Contraception After Liver Transplantation

Jabiry-Zieniewicz, Zoulikha; Bobrowska, Katarzyna; Kamiński, Paweł; Wielgoś, Mirosław; Zieniewicz, Krzysztof; Krawczyk, Marek

doi:10.1016/j.transproceed.2007.02.063

Cited by 60 publications

(34 citation statements)

References 7 publications

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“…Variations in CK and AST activities were reported to be associated with liver and heart disease (30,31). However, the present study revealed that activity levels of the two enzymes differed between the in vivo and in vitro experiments; in addition, activity levels of AST and CK in the supernatants of heat-stressed H9c2 cells as well as the sera of the heat-stressed rats exhibited significant variations.…”

Section: Discussioncontrasting

confidence: 69%

Localization and expression of heat shock protein 70 with rat myocardial cell damage induced by heat stress in vitro and in vivo

Chen

Adam

Cheng

et al. 2014

Molecular Medicine Reports

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The aim of the present study was to investigate the association between heat shock protein (Hsp) 70 expression kinetics and heat stress‑induced damage to rat myocardial cells in vitro and in vivo. The results showed that the activity of heart injury‑associated enzymes, including aspartate aminotransferase and creatine kinase, significantly increased and myocardial cells developed acute histopathological lesions; this therefore suggested that heat stress altered the integrity of myocardial cells in vitro and in vivo. Levels of Hsp70 in vitro decreased following the initiation of heat stress and then steadily increased until heat stress ceased at 100 min; however, in vivo studies demonstrated a gradual increase in Hsp70 levels in the heart cells of rats from the initiation of heat stress, followed by a sharp decline at 100 min. These results indicated that the cells sustained different degrees of injury in vivo compared with those sustained in vitro, this may be due to different regulatory mechanisms in the two environments. Intracytoplasmic Hsp70 signaling was significantly reduced at 60 min in vitro, compared with that of the in vivo study, indicating that Hsp70 consumption may have exceeded its production prior to 60 min of heat stress, and following 60 min the cells produced sufficient Hsp70 protein for their protection against heat stress. Hsp70‑positive signals in the cytoplasm of heart cells in vivo were more prominent in the intact areas compared with those of the degenerated areas and the density of Hsp70‑positive signals was significantly reduced following 60 min of heat stress. In conclusion, comprehensive comparisons of enzymes, cell morphology and Hsp70 levels indicated that decreased levels of Hsp70 were associated with the reduced protective effect on myocardial cells in vitro and in vivo.

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Section: Discussioncontrasting

confidence: 69%

Localization and expression of heat shock protein 70 with rat myocardial cell damage induced by heat stress in vitro and in vivo

Chen

Adam

Cheng

et al. 2014

Molecular Medicine Reports

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“…Therefore, the integrity of cellular structure may be altered during the course of transportation (Witek et al, 1996). The presence of ALT and AST enzyme activities in blood serum are often associated with liver and heart disease (Jabiry-Zieniewicz et al, 2007;Radosavljević et al, 2008). Therefore, these enzymes can be monitored to evaluate stress in pigs during transportation.…”

Section: Discussionmentioning

confidence: 99%

Variation in Hsp90, HSF-1, and hsp90 mRNA expression in tissues of pigs exposed to different durations of transport

Yue

Tang

et al. 2010

Livestock Science

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“…Patients who have established normal organ function and are stable at least 6 to 8 months after transplantation can use any of the currently available hormonal contraceptives, provided they do not have other contraindications to the estrogen component. 58,254,257,[258][259][260] Contraindications to estrogen, however, occur more commonly in transplant recipients. For example, COCs should not be prescribed to patients with active liver dysfunction or coronary artery disease.…”

Section: Adolescent Recipients Of Solid Organ Transplantationmentioning

confidence: 99%

Contraception for Adolescents

Ott

Sucato²

2014

Pediatrics

245

133

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A working knowledge of contraception will assist the pediatrician in both sexual health promotion as well as treatment of common adolescent gynecologic problems. Best practices in adolescent anticipatory guidance and screening include a sexual health history, screening for pregnancy and sexually transmitted infections, counseling, and if indicated, providing access to contraceptives. Pediatricians’ long-term relationships with adolescents and families allow them to help promote healthy sexual decision-making, including abstinence and contraceptive use. Additionally, medical indications for contraception, such as acne, dysmenorrhea, and heavy menstrual bleeding, are frequently uncovered during adolescent visits. This technical report provides an evidence base for the accompanying policy statement and addresses key aspects of adolescent contraceptive use, including the following: (1) sexual history taking, confidentiality, and counseling; (2) adolescent data on the use and side effects of newer contraceptive methods; (3) new data on older contraceptive methods; and (4) evidence supporting the use of contraceptives in adolescent patients with complex medical conditions.

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Low-Dose Hormonal Contraception After Liver Transplantation

Cited by 60 publications

References 7 publications

Localization and expression of heat shock protein 70 with rat myocardial cell damage induced by heat stress in vitro and in vivo

Localization and expression of heat shock protein 70 with rat myocardial cell damage induced by heat stress in vitro and in vivo

Variation in Hsp90, HSF-1, and hsp90 mRNA expression in tissues of pigs exposed to different durations of transport

Contraception for Adolescents

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