Recently, nanomaterial-based scintillators are newly emerging technologies for many research fields, including medical imaging, nuclear security, nuclear decommissioning, and astronomical applications, among others. To date, scintillators have played pivotal roles in the development of modern science and technology. Among them, plastic scintillators have a low atomic number and are mainly used for beta-ray measurements owing to their low density, but these types of scintillators can be manufactured not in large sizes but also in various forms with distinct properties and characteristics. However, the plastic scintillator is mainly composed of C, H, O and N, implying that the probability of a photoelectric effect is low. In a gamma-ray nuclide analysis, they are used for time-related measurements given their short luminescence decay times. Generally, inorganic scintillators have relatively good scintillation efficiency rates and resolutions. And there are thus widely used in gamma-ray spectroscopy. Therefore, developing a plastic scintillator with performance capabilities similar to those of an inorganic scintillator would mean that it could be used for detection and monitoring at radiological sites. Many studies have reported improved performance outcomes of plastic scintillators based on nanomaterials, exhibiting high-performance plastic scintillators or flexible film scintillators using graphene, perovskite, and 2D materials. Furthermore, numerous fabrication methods that improve the performance through the doping of nanomaterials on the surface have been introduced. Herein, we provide an in-depth review of the findings pertaining to nanomaterial-based scintillators to gain a better understanding of radiological detection technological applications.