Low-energy electron interactions with liquid water and energy depositions in nanometric volumes

Can Monte Carlo track structure codes reveal reaction mechanism in DNA damage and improve radiation therapy?

“…4 updates (and extends down to 10 eV) the compilation of inelastic cross-sections for liquid/solid water presented in Emfietzoglou and Nikjoo (2007) which should be consulted for the relevant references. Results not included in our previous figure are those of Ritchie et al (1978), Kaplan and Sukhonosov (1991), Tomita et al (1997), Emfietzoglou et al (2003), Timneanu et al (2004), Tan et al (2004), and a recent revision by Tung et al (2007) of their earlier calculations. The present figure also includes calculations with the latest version of the analytic general-purpose formula (TPP-2M) developed at NIST which is also recommended for organic and, generally, low-density materials (Tanuma et al, 1993;Powell et al, 2005).…”

A physical palette for ion-beam cancer therapy

“…Many chemical reactions take place as well; they are also important for estimates of the DNA damage since they define the agents interacting with the DNA. Again, this aspect has attracted plenty of attention of Monte Carlo simulations adepts [5] who, using various SDCS of ionization (including the effects of the medium [6][7][8][9]), trace the electrons and other species through the medium up to their interaction with the DNA. We developed an approach to calculations that can be done on this scale without using Monte Carlo simulations [10,11].…”

“…We also use mean free paths of electrons taken from Ref. [8] and obtain the number of electrons crossing the surface of a cylinder, which represent a single convolution of a DNA molecule. is number multiplied by the probability of a SSB gives the number of SSB's per DNA convolution per ion.…”

Semi-empirical dielectric descriptions of the Bethe surface of the valence bands of condensed water

“…(3b) resembles the plasmon dispersion of the free-electron gas at small-q. Recent applications of the above version of the Ritchie and Howie model may be found in Leger et al [19], Akkerman et al [20] and Tung et al [21]. For condensed water, the availability of experimental data for all dielectric function representations, namely, ReðeÞ ¼ e 1 ; ImðeÞ ¼ e 2 and Im À1=e ð Þ, has motivated the development of somewhat more elaborate representations of its dielectric response properties where basic band structure characteristics are accounted for [12][13][14][15][16]22].…”