In order to investigate the screening effect of a nuclear reaction in a liquid metal environment, thick-target yields of the 6 Li(d,) 4 He and 7 Li(p,) 4 He reactions were measured using a liquid Li target for incident energies between 22.5 and 70 keV. The modified SðEÞ factor [S Ã ðEÞ] for the liquid Li environment was deduced by dividing the measured yield by the energy integration of the penetration factor divided by the stopping power. It was shown that S Ã ðEÞ for the liquid environment is considerably larger than that for the atomic/molecular environment for both reactions. The difference in the screening energy between the two environments was deduced to be ÁU ¼ 235 AE 63 ( 6 Li+d) and 140 AE 82 eV ( 7 Li+p), although the screening energy for liquid Li has a large uncertainty with U liq $ 486{776 ( 6 Li+d) and 324-637 eV ( 7 Li+p) owing to the uncertainty of the astrophysical bare SðEÞ factors. This difference in the screening energy should be considered in such a way that, in liquid Li metal, conduction electrons and Li þ ions contribute to the screening in addition to bound electrons.