Low event rate for stress-only perfusion imaging in patients evaluated for chest pain

Gibson, Peter B.; Demus, Diane; Noto, Richard B.; Hudson, William A.; Johnson, Lynne L.

doi:10.1016/s0735-1097(02)01720-5

Cited by 98 publications

(33 citation statements)

References 10 publications

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“…The overall event rate during the follow-up period in these patients was 0.6%. Two other studies in preliminary form encompassing 927 total patients demonstrated even lower event rates (< 0.2%) [46,48]. This stress-only protocol applied to relatively low-risk patients is a safe and effective means of reducing costs while improving laboratory efficiency.…”

Section: Stress-only Imagingmentioning

confidence: 82%

“…This stress-only protocol applied to relatively low-risk patients is a safe and effective means of reducing costs while improving laboratory efficiency. AC SPECT imaging extends the application of this protocol to a significantly larger patient population [48].…”

Section: Stress-only Imagingmentioning

confidence: 95%

“…Without the rest images and the inability to calculate poststress LV dilation, there is a concern that patients with balanced/high-risk three-vessel or LM disease might be missed. However, several studies have demonstrated the safety and efficacy of the stress-only approach [46,48,49].…”

Section: Stress-only Imagingmentioning

confidence: 99%

“…Gibson et al [48] followed 652 patients for a mean of 22.3 ± 6.4 months following stress-only imaging. Of these patients, 37% would have required rest images because of various attenuation artifacts, but did not because of normal attenuation-corrected studies.…”

Section: Stress-only Imagingmentioning

confidence: 99%

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Attenuation correction for single photon emission computed tomography myocardial perfusion imaging

Corbett

Kritzman²,

Ficaro³

2004

Curr Cardiol Rep

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The specificity of cardiac single photon emission computed tomography (SPECT) perfusion imaging is significantly affected by internal photon absorption. Commonly referred to as anterior wall breast and inferior wall diaphragm attenuation artifacts, even when following characteristic patterns in women and men, the reduced activity produced can be difficult to differentiate from real perfusion defects. Unfortunately, wide variations in body habitus result in unpredictable variations in tissue attenuation and the specificity of uncorrected SPECT is unacceptably low in many laboratories. This manuscript reviews recent developments in attenuation correction methods for cardiac SPECT. Several commercial methods are now available, and although the initial success using these methods varied widely, as these methods have been improved successful clinical reports are appearing with increasing frequency. Recent developments have yielded more robust validated methods and significant clinical advantages have been achieved in the diagnostic evaluation of coronary heart disease (sensitivity as well as specificity) and myocardial viability. As these methods continue to mature, further advances should be anticipated.

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Section: Stress-only Imagingmentioning

confidence: 82%

Section: Stress-only Imagingmentioning

confidence: 95%

Section: Stress-only Imagingmentioning

confidence: 99%

Section: Stress-only Imagingmentioning

confidence: 99%

See 2 more Smart Citations

Attenuation correction for single photon emission computed tomography myocardial perfusion imaging

Corbett

Kritzman²,

Ficaro³

2004

Curr Cardiol Rep

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show abstract

“…Most of the previous studies found a satisfactory agreement between the results of gated stress-only SPECT and that of the standard protocol [2], however, the limitation of the gated stress-only SPECT is that, without attenuation correction, it can confuse the diagnostician, who may misinterpret an attenuation artifact in a stress study of a normal patient as an ischemic event of a patient with CAD [2,13,14].…”

Section: Discussionmentioning

confidence: 94%

Single Tc99m Sestamibi injection, double acquisition gated SPECT after stress and during low-dose dobutamine infusion: a new suggested protocol for evaluation of myocardial perfusion

Fallahi

Beiki

Gholamrezanezhad

et al. 2008

Int J Cardiovasc Imaging

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Our proposed protocol demonstrates good correlation and agreement with standard method and even is superior in some cases especially for estimation of viability after MI. Regarding no need for the rest phase radiotracer injection and imaging, this protocol can be more convenient (except the need for close monitoring of the patient during LDD infusion), less time-consuming, less expensive and moreover with less radiation burden to the patients and personnel.

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Assessment of Patients with Suspected Coronary Artery Disease

Ruffin

Heller

2012

Handbook of Nuclear Cardiology

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Low event rate for stress-only perfusion imaging in patients evaluated for chest pain

Abstract: These results support stress-only imaging in patients with low to medium probability for CAD as a safe, time- and cost-efficient imaging modality.

Cited by 98 publications

References 10 publications

Attenuation correction for single photon emission computed tomography myocardial perfusion imaging

Attenuation correction for single photon emission computed tomography myocardial perfusion imaging

Single Tc99m Sestamibi injection, double acquisition gated SPECT after stress and during low-dose dobutamine infusion: a new suggested protocol for evaluation of myocardial perfusion

Assessment of Patients with Suspected Coronary Artery Disease

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