1996
DOI: 10.1002/(sici)1099-0496(199601)21:1<48::aid-ppul8>3.0.co;2-m
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Low flow oxygen delivery via nasal cannula to neonates

Abstract: Neonates with chronic lung disease often require oxygen in the neonatal intensive care unit. The purpose of this study was to determine (1) the actual inspired oxygen concentration (F1O2) delivered to neonates when using a low‐flow flowmeter and a nasal cannula, and (2) the accuracy with which F1O2 could be estimated using a formula that we developed. We studied two groups of infants: 18 infants less than 1,500 g and 13 infants greater than 1,500 g. We measured pharyngeal oxygen levels by sampling pharyngeal g… Show more

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Cited by 54 publications
(39 citation statements)
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“…3,4 In addition, using the lowest flow possible minimizes irritation from drying of the nasal passage. 5 The literature also guided the development of a chart to calculate the O 2 level delivered to the hypopharynx (FHO 2 ) from patient weight, NC flow, and FIO 2 . 3,4,6,8 Using a number of assumptions, the mathematical calculation can be simplified to (0.21 ϩ [flow/ weight] ϫ [FNCO 2 Ϫ 0.21]), where FNCO 2 is the FIO 2 set to be delivered via the NC (Appendix 1).…”
Section: Resultsmentioning
confidence: 99%
See 1 more Smart Citation
“…3,4 In addition, using the lowest flow possible minimizes irritation from drying of the nasal passage. 5 The literature also guided the development of a chart to calculate the O 2 level delivered to the hypopharynx (FHO 2 ) from patient weight, NC flow, and FIO 2 . 3,4,6,8 Using a number of assumptions, the mathematical calculation can be simplified to (0.21 ϩ [flow/ weight] ϫ [FNCO 2 Ϫ 0.21]), where FNCO 2 is the FIO 2 set to be delivered via the NC (Appendix 1).…”
Section: Resultsmentioning
confidence: 99%
“…The literature provided evidence for the clinical practice of NC use [2][3][4][5][6][7][8][9][10] ; however, obstacles still remained when introducing this practice into the clinical service. The process of developing and introducing standard NC orders was approached using a quality improvement (QI) model.…”
mentioning
confidence: 99%
“…30,31 In clinical studies, hypopharyngeal oxygen concentrations have been shown to be reliable measures of the actual inspired oxygen concentrations. [32][33][34][35][36][37][38] If hypopharyngeal oxygen concentrations need to be decreased from those achieved with the 100% oxygen source, an entrainment device would be useful in those situations.…”
Section: Figurementioning
confidence: 99%
“…Standard or low-flow NC therapy has been limited by inadequate humidification and the drying effect on upper airway mucosa, and for infants has a variably defined upperlimit of 0.5-2 l/min (l.p.m.). 7,8 Nasal mucosal injury and bleeding have also been associated with unheated NC flow (1 l.p.m. ), although overly aggressive suctioning of the nares may contribute as well.…”
Section: 2mentioning
confidence: 99%