Low fouling aptasensing of rivaroxaban in real samples using poly (toluidine blue) decorated by silver nanoparticle: A new platform for the cardiovascular disease analysis

Ebrahimi, Rokhsareh; Hasanzadeh, Mohammad; Rashidi, Mohammad‐Reza; Jouyban, Abolghasem

doi:10.1016/j.microc.2023.108529

Cited by 7 publications

(2 citation statements)

References 65 publications

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“…The calibration curve demonstrated linearity within the 10-600 nM concentration range in plasma and exhaled breath condensate samples. A similar approach was designed using ITO-PET modified by polytoluidine blue, silver nanoparticles, and polyethylene glycol as electrode substrates and aptamers as rivaroxaban-recognising elements [89]. This sensor showed 6.65 and 4.13 nM detection limits for the plasma and exhaled breath condensate samples.…”

Section: Electrochemical Sensors For Anticoagulants Using Modified El...mentioning

confidence: 99%

Electrochemical Monitoring in Anticoagulation Therapy

Mruthunjaya,

Torriero

2024

Molecules

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The process of blood coagulation, wherein circulating blood transforms into a clot in response to an internal or external injury, is a critical physiological mechanism. Monitoring this coagulation process is vital to ensure that blood clotting neither occurs too rapidly nor too slowly. Anticoagulants, a category of medications designed to prevent and treat blood clots, require meticulous monitoring to optimise dosage, enhance clinical outcomes, and minimise adverse effects. This review article delves into the various stages of blood coagulation, explores commonly used anticoagulants and their targets within the coagulation enzyme system, and emphasises the electrochemical methods employed in anticoagulant testing. Electrochemical sensors for anticoagulant monitoring are categorised into two types. The first type focuses on assays measuring thrombin activity via electrochemical techniques. The second type involves modified electrode surfaces that either directly measure the redox behaviours of anticoagulants or monitor the responses of standard redox probes in the presence of these drugs. This review comprehensively lists different electrode compositions and their detection and quantification limits. Additionally, it discusses the potential of employing a universal calibration plot to replace individual drug-specific calibrations. The presented insights are anticipated to significantly contribute to the sensor community’s efforts in this field.

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Section: Electrochemical Sensors For Anticoagulants Using Modified El...mentioning

confidence: 99%

Electrochemical Monitoring in Anticoagulation Therapy

Mruthunjaya,

Torriero

2024

Molecules

View full text Add to dashboard Cite

show abstract

“…The calibration curve demonstrated linearity within the 10 -600 nM concentration range in plasma and exhaled breath condensate samples. A similar approach has been designed using ITO-PET modified by polytoluidine blue, silver nanoparticles, and polyethylene glycol as electrode substrates and aptamers as rivaroxaban-recognising elements [89]. This sensor showed 6.65 nM and 4.13 nM detection limits for plasma and exhaled breath condensate samples.…”

Section: Electrochemical Sensors For Anticoagulants Using Modified El...mentioning

confidence: 99%

Electrochemical Monitoring on Anticoagulation Therapy

Mruthunjaya,

Torriero

2024

Preprint

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The process of blood coagulation, wherein circulating blood transforms into a clot in response to internal or external injury, is a critical physiological mechanism. Monitoring this coagulation process is vital to ensure that blood clotting occurs neither too rapidly nor too slowly. Anticoagulants, a category of medications designed to prevent and treat blood clots, require meticulous monitoring to optimise dosage, enhance clinical outcomes, and minimise adverse effects. This review article delves into the various stages of blood coagulation, explores commonly used anticoagulants and their targets within the coagulation enzyme system, and emphasises the electrochemical methods employed in anticoagulant testing. Electrochemical sensors for anticoagulant monitoring are categorised into two types. The first type focuses on assays measuring thrombin activity via electrochemical techniques. The second type involves modified electrode surfaces that either directly measure the redox behaviour of anticoagulants or monitor the response of standard redox probes in the presence of these drugs. The review provides a comprehensive list of different electrode compositions and their detection and quantification limits. Additionally, it discusses the potential of employing a universal calibration plot to replace individual drug-specific calibrations. The insights presented are anticipated to significantly contribute to the sensor community's efforts in this field.

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A disposable impedimetric immunosensor for the analysis of CA125 in human serum samples

Yılmaz,

Bilgi

2024

Biomed Microdevices

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Low fouling aptasensing of rivaroxaban in real samples using poly (toluidine blue) decorated by silver nanoparticle: A new platform for the cardiovascular disease analysis

Cited by 7 publications

References 65 publications

Electrochemical Monitoring in Anticoagulation Therapy

Electrochemical Monitoring in Anticoagulation Therapy

Electrochemical Monitoring on Anticoagulation Therapy

A disposable impedimetric immunosensor for the analysis of CA125 in human serum samples

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