Slippery liquid-infused porous surface (SLIPS), inspired
by the Nepenthes pitcher plant, exhibits excellent
performances
as it has a smooth surface and extremely low contact angle hysteresis.
Biomimetic SLIPS attracts considerable attention from the researchers
for different applications in self-cleaning, anti-icing, anticorrosion,
antibacteria, antithrombotic, and other fields. Hence, SLIPS has shown
promise for applications across both the biomedical and industrial
fields. However, the manufacturing of SLIPS with strong bonding ability
to different substrates and powerful liquid locking performance remains
highly challenging. In this review, a comprehensive overview of research
on SLIPS for medical applications is conducted, and the design parameters
and common fabrication methods of such surfaces are summarized. The
discussion extends to the mechanisms of interaction between microbes,
cells, proteins, and the liquid layer, highlighting the typical antifouling
applications of SLIPS. Furthermore, it identifies the potential of
utilizing the controllable factors provided by SLIPS to develop innovative
materials and devices aimed at enhancing human health.