Low-grade central osteosarcoma of the mandible clinically mimicking a benign fibro-osseous lesion: A rare case report

Osteosarcoma of the mandible: A case with a clinical appearance similar to benign lesions

“…In their case report, Arnold et al concluded in 2020 that osteosarcoma can be easily confused with benign fibrous lesions such as fibrosing dysplasia, cemento-osseous dysplasia and ossifying fibroma, especially in cases of low-grade osteosarcoma where osteoid is barely visible on histopathological appearance. 15 Because of the potential clinical and radiographic similarities between osteosarcoma and reactive lesions, clinicians should exercise caution in diagnosis and adopt an appropriate and timely approach. The decisions should be made as a team including Oral and maxillofacial medicine specialists, Oral and maxillofacial radiologists and pathologists, Oral and maxillofacial surgeons.…”

“…On the other hand, early‐stage osteosarcoma can be mistaken for other benign lesions. In their case report, Arnold et al concluded in 2020 that osteosarcoma can be easily confused with benign fibrous lesions such as fibrosing dysplasia, cemento‐osseous dysplasia and ossifying fibroma, especially in cases of low‐grade osteosarcoma where osteoid is barely visible on histopathological appearance 15 …”