Low-grade myofibroblastic sarcoma of the tongue

Jay, Amrita; Piper, Kim; Farthing, Paula M.; Carter, John; Diwakar, Anitha

doi:10.1016/j.tripleo.2007.06.004

Cited by 39 publications

(30 citation statements)

References 24 publications

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“…Low-grade myofibroblastic sarcoma (LGMS) is a neoplasm of the soft tissue characterized by myofibroblastic differentiation, which may occur anywhere in the body but frequently occurs in the head and neck region (1,2). Of those, the most common was the tongue (1).…”

Section: Introductionmentioning

confidence: 99%

Indolent growth of low-grade myofibroblastic sarcoma of the cheek mimics benign lesions: A case report and literature review

et al. 2017

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Low-grade myofibroblastic sarcoma (LGMS) is a neoplasm of the soft tissue characterized by myofibroblastic differentiation. This type of tumor has been observed in various sites in the whole body, but frequently occurs in the head and neck region. It typically presents as a slow-growing painless mass, which is often mistaken for a benign lesion due to its indolent growth; however, LGMS is a malignant neoplasm. In the present study, a 43-year-old female presented with a 14-mm LGMS lesion in the buccal subcutaneous tissues of the buccinator muscle. The patient had initially noticed the lesion 2-months prior to presenting at the hospital. Following biopsy, the tumor was surgically resected and no recurrence or metastasis was observed during a follow-up time of 2 years. To the best of our knowledge, this case is the first report of LGMS located in the buccal subcutaneous tissue of the buccinator muscle. The present study a literature review of 55 cases of this tumor type in the head and neck region was conducted, revealing that the indolent growth of these lesions may contribute to a delay in diagnosis. The average time between the onset of clinical symptoms and hospital admission is 3.9 months, and this form of tumor is frequently misdiagnosed as a benign lesion. Therefore, the present study suggests that an incisional biopsy may be performed to rule out LGMS when clinicians encounter patients with the aforementioned indolent lesions anywhere in the body. In addition, the avoidance of radiotherapy is recommended following resection of the LGMS tumor, as it may induce LGMS recurrence.

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Section: Introductionmentioning

confidence: 99%

Indolent growth of low-grade myofibroblastic sarcoma of the cheek mimics benign lesions: A case report and literature review

et al. 2017

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“…About 20 cases have been reported in the oral cavity, especially in the tongue and bone,1 while gingiva as the primary site has been described only once so far 2…”

Section: Discussionmentioning

confidence: 99%

“…A painless, slow-growing mass with a relatively indolent course is the most common clinical presentation,1 3 and the frequent absence of a detectable epithelial discontinuity raises the risk of delay in diagnosis and subsequent worsening prognosis.…”

Section: Discussionmentioning

confidence: 99%

Low-grade myofibroblastic sarcoma of the gingiva

Montebugnoli¹,

Venturi

Gissi

et al. 2010

Case Reports

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SummaryLow-grade myofibroblastic sarcoma is a malignant tumour from myofibroblasts, which has only recently become clearly defined. It represents a rare entity developing in the soft tissues of the head and neck. About 20 cases have been reported in the oral cavity, especially in the tongue and bone, while gingiva as the primary site has been described only once to date. Diagnostic methods include histology and immunohistochemistry.The present report concerns a case of a 37-year-old man who presented with a persistent gingival ulcerated swelling that was interpreted for a long time as a gingival epulis. A low-grade myofibrosarcoma was diagnosed and the patient underwent a segmental osteotomy of the mandibular symphisys for complete excision. There was no sign of recurrence or metastatic disease during the 18-month postoperative period. BACKGROUND

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“…The fibrosarcoma is characterized by high local recurrence rate and a low incidence of locoregional lymph node and/or distant hematogenous metastases [27]. Myxofibrosarcoma is one of its variety with fibrotic myxoid elements.…”

Section: Fibrosarcoma (1 Case)mentioning

confidence: 99%

Diagnosis and Treatment of Head and Neck Sarcomas: Personal Experiences

Laus¹

2013

JCTR

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Sarcomas are a rare group of tumors. They do not commonly manifest as malignancies in the head and neck region. The rare nature of these tumors has resulted in a limited number of publications. This is a descriptive study. We included patients with primary sarcomas of the head and neck, observed between 1991 and 2011 in the department of Otorhinolaryngology (University of Chieti, Italy). We studied the following variables: age, gender, race, origin, primary anatomical location of the neoplasm, pathology, diagnosis and type of cancer treatment employed. During the study period, we found 9 patients with head and neck sarcomas. Of this sample, 6 were males, and 3 were females. The man/woman ratio was 2:1. As far as age is concerned, the most affected age range was between 60 and 80 years. The mean age of the patients was 62. As far as pathology is concerned, we found 7 histopathological variations of sarcomas, and the most common type was the leiomyosarcoma. The most widely used treatment modality was surgical treatment. The data in this study show that head and neck sarcomas are rare tumors with high histological variability, which may involve different anatomical sites. Since these are rare and not well-known lesions, further epidemiological studies must be carried out, in order to give us more knowledge about the disease.

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Low-grade myofibroblastic sarcoma of the tongue

Cited by 39 publications

References 24 publications

Indolent growth of low-grade myofibroblastic sarcoma of the cheek mimics benign lesions: A case report and literature review

Indolent growth of low-grade myofibroblastic sarcoma of the cheek mimics benign lesions: A case report and literature review

Low-grade myofibroblastic sarcoma of the gingiva

Diagnosis and Treatment of Head and Neck Sarcomas: Personal Experiences

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