1995
DOI: 10.1016/0735-1097(95)00267-1
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Low intensity exercise training in patients with chronic heart failure

Abstract: Patients with stable chronic heart failure can achieve significant improvement in functional capacity from a low intensity exercise training regimen. The mechanism responsible for this favorable effect involves an increase in mitochondrial density, which reflects an improvement in oxidative capacity of trained skeletal muscles.

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Cited by 281 publications
(172 citation statements)
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References 33 publications
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“…While available evidence has demonstrated cardioprotective benefits associated with exercise among high-risk cardiac populations [4][5][6][7][8], safety research necessitates a search for "rare events" which may require a population surveillance approach to acquire larger numbers of ICD patients. Large international consortiums that enroll ICD patients with primary survey data are likely required to determine how event rates during exercise compare incrementally with what might be expected at resting states.…”
Section: Discussionmentioning
confidence: 99%
See 1 more Smart Citation
“…While available evidence has demonstrated cardioprotective benefits associated with exercise among high-risk cardiac populations [4][5][6][7][8], safety research necessitates a search for "rare events" which may require a population surveillance approach to acquire larger numbers of ICD patients. Large international consortiums that enroll ICD patients with primary survey data are likely required to determine how event rates during exercise compare incrementally with what might be expected at resting states.…”
Section: Discussionmentioning
confidence: 99%
“…As such, their use worldwide is increasing for both primary and secondary prevention of sudden cardiac death [3]. Exercise and cardiac rehabilitation also has established benefits in survival, health status, and quality of life in both high and low risk cardiac patients, including those with and without an ICD [4][5][6][7][8]. However, those with an ICD are underrepresented in cardiac rehabilitation, typically report low levels of exercise [9,10] and are often reluctant to participate in exercise programs due to fear of exercise-induced shocks [11,12].…”
Section: Introductionmentioning
confidence: 99%
“…Physical training at submaximal levels in HF has no significant effect on cardiac output, 24,25,26 but a slight improvement at the peak of exercise. 20,25 Hambrecht et al, 20 on the other hand, observed reductions in the final left ventricular diastolic diameter (LVDD), suggesting a reverse remodeling induced by physical training.…”
Section: Central Cardiac Effectsmentioning
confidence: 99%
“…Physical training can improve the mitochondrial volume with improvement of oxidative metabolism. 24,29,30 Reduced skeletal muscle mass has been verified in patients with HF and has been related to a reduction in exercise capacity. 31,32 The inversion of change from type IIb skeletal muscle fibers (anaerobic) to type I skeletal muscle fibers (aerobic) was also demonstrated, and this adaptive response is associated with an improvement in exercise capacity.…”
Section: Peripheral Effectsmentioning
confidence: 99%
“…Meta-regression analysis from 2016 (Uddin et al, 2016) on predictors of exercise capacity following exercise-based rehabilitation in patients with coronary heart disease and heart failure included trials in which exercise frequency ranged from 3 to 4 days per week (mean: 3,6), training bout duration ranged from 35 to 47 minutes (mean: 41 minutes), training protocol duration lasted from 22 to 31 months (mean: 27) and exercise intensity ranged from 50 to 85% of Hrmax and VO 2 max (Uddin et al, 2016). Interestingly, low-intensity CR (40% VO 2 max) for 8 wk, 3 days per week could be effective in some patients (Belardinelli, Georgiou, Scocco, Barstow, Purcaro, 1995).…”
Section: Agnieszka Kujawska Et Almentioning
confidence: 99%