Low keV portal venous phase as a surrogate for pancreatic phase in a pancreatic protocol dual-energy CT: feasibility, image quality, and lesion conspicuity

Noda, Yoshifumi; Tochigi, Toru; Parakh, Anushri; Joseph, Evita; Hahn, Peter F.; Kambadakone, Avinash

doi:10.1007/s00330-021-07744-w

Cited by 16 publications

(6 citation statements)

References 34 publications

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“…The delay times for each phase after contrast agent injection were as follows: arterial phase, 40 s; portal venous phase, 70 s; and delayed phase, 180 s. Non-contrast and portal venous phase images were evaluated during this study because the highest numerical value could be obtained by dynamic CT imaging during the portal venous phase to visualise a hypo-vascular tumour. 6,7 All the phase images were reconstructed with the standard kernel using the ASiR-V algorithm (GE Healthcare, Waukesha, WI, USA) at level of 30%. Images obtained using VMI with seven energy levels (40/50/60/70/80/90/100 keV) were reconstructed axially in 2.5-mm slices using a gemstone spectral imaging viewer (GE Healthcare).…”

Section: Methodsmentioning

confidence: 99%

Evaluation of virtual monochromatic imaging with dual-energy computed tomography of small liver metastases from malignant abdominal tumours: Quantitative and qualitative analyses

Okada,

Matsunaga,

Yamamoto

et al. 2023

Acta Radiologica Open

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Background The assessment of small metastatic liver tumours using dual-energy computed tomography (DECT) has not been fully established. Purpose To assess the effect of low-keV virtual monochromatic imaging (VMI) with non-contrast and contrast-enhanced DECT on the qualitative and quantitative image parameters of small liver metastases. Material and methods Two radiologists retrospectively evaluated 92 metastatic liver tumours (5–20 mm) in 32 patients. Non-contrast and contrast-enhanced VMI were reconstructed at seven energy levels (40–100 keV) with 10-keV intervals. Lesion boundary, lesion delineation, image noise, and overall image quality were evaluated using the visual analogue scale. A high subjective score indicates good overall image quality, clear nodal boundaries and delineation, and less noticeable image noise. Subjective scores were compared using the Kruskal–Wallis test. A quantitative analysis involving the signal-to-noise ratio (SNR) and contrast-to-noise ratio (CNR) was performed. Results The lesion boundary was highest at 40 keV and significantly improved during the non-contrast portal venous phase compared to that at higher keV ( p < .005). The lesion delineation score was significantly higher at 40 keV and tended to decrease at higher keV. Image noise and overall image quality were rated low at low keV; however, those at 80, 90, and 100 keV were rated the highest ( p < .005). The CNR and SNR were highest for non-contrast CT at 100 keV. During the portal venous phase, no significant differences were observed in CNR and SNR at each keV. Conclusion Low-keV imaging using non-contrast and contrast-enhanced DECT is useful for delineating small hepatic metastatic tumours.

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Section: Methodsmentioning

confidence: 99%

Evaluation of virtual monochromatic imaging with dual-energy computed tomography of small liver metastases from malignant abdominal tumours: Quantitative and qualitative analyses

Okada,

Matsunaga,

Yamamoto

et al. 2023

Acta Radiologica Open

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“…However, it should be noted that other keV reconstructions (e. g. 70 keV) are more suitable in highly vascularized tissue (e. g. renal parenchyma) [20][21][22]. A number of studies were able to show the advantage of these two spectral CT reconstructions for malignancies in the head-neck/neck region for primary and secondary hepatic masses and pancreatic malignancies in which the lesion-to-tissue contrast is intrinsically lower [23]. For example, in the case of hepatic steatosis, either medically (e. g. during chemotherapy) or metabolically induced, it is often challenging to detect faint hypovascularized lesions on conventional CT. By using low-energy VMI images or iodine maps, improved lesion-to-tissue contrast can be achieved because the lesion has a greater density while the fatty liver tissue appears hypodense.…”

Section: Improved Detection Of Oncological Lesionsmentioning

confidence: 99%

“…70 keV) besser eignen[20][21][22]. Eine Vielzahl an Studien konnte den Vorteil dieser beiden Spektral-CT-Rekonstruktionen für Malignome aus dem Kopf-/Hals-Bereich, für primär und sekundär hepatische Raumforderungen sowie Pankreasmalignome demonstrieren, bei denen der Läsion-zu-Gewebe-Kontrast intrinsisch niedrig ist[23]. Bespielweise stellt eine Steatosis hepatis, entweder medikamentös (z.…”

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Spectral CT in Oncology

Sauerbeck

Adam

Meyer

2022

Rofo

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Background Spectral CT is gaining increasing clinical importance with multiple potential applications, including oncological imaging. Spectral CT-specific image data offers multiple advantages over conventional CT image data through various post-processing algorithms, which will be highlighted in the following review. Methodology The purpose of this review article is to provide an overview of potential useful oncologic applications of spectral CT and to highlight specific spectral CT pitfalls. The technical background, clinical advantages of primary and follow-up spectral CT exams in oncology, and the application of appropriate spectral tools will be highlighted. Results/Conclusions Spectral CT imaging offers multiple advantages over conventional CT imaging, particularly in the field of oncology. The combination of virtual native and low monoenergetic images leads to improved detection and characterization of oncologic lesions. Iodine-map images may provide a potential imaging biomarker for assessing treatment response. Key Points: Citation Format

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“…The proposed portal venous phase protocol with a single DECT acquisition was found to have comparable diagnostic performance and the added benefit of radiation dose reduction. 20…”

Section: Dual-energy Computed Tomography: Pancreatic Protocolsmentioning

confidence: 99%

Dual-Energy CT in the Pancreas

Mroueh

Cao

Kambadakone

2022

Journal of Gastrointestinal and Abdominal Radiology

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Dual-energy computed tomography (DECT) is an evolving imaging technology that is gaining popularity, particularly in different abdominopelvic applications. Essentially, DECT uses two energy spectra simultaneously to acquire CT attenuation data which is used to distinguish among structures with different tissue composition. The wide variety of reconstructed image data sets makes DECT especially attractive in pancreatic imaging. This article reviews the current literature on DECT as it applies to imaging the pancreas, focusing on pancreatitis, trauma, pancreatic ductal adenocarcinoma, and other solid and cystic neoplasms. The advantages of DECT over conventional CT are highlighted, including improved lesion detection, radiation dose reduction, and enhanced image contrast. Additionally, data exploring the ideal protocol for pancreatic imaging using DECT is reviewed. Finally, limitations of DECT in pancreatic imaging as well as recommendations for future research are provided.

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Low keV portal venous phase as a surrogate for pancreatic phase in a pancreatic protocol dual-energy CT: feasibility, image quality, and lesion conspicuity

Cited by 16 publications

References 34 publications

Evaluation of virtual monochromatic imaging with dual-energy computed tomography of small liver metastases from malignant abdominal tumours: Quantitative and qualitative analyses

Evaluation of virtual monochromatic imaging with dual-energy computed tomography of small liver metastases from malignant abdominal tumours: Quantitative and qualitative analyses

Spectral CT in Oncology

Dual-Energy CT in the Pancreas

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