Low Knowledge of HIV PrEP Within a Midwestern US Cohort of Persons who Inject Drugs

Sayood, Sena; Marks, Laura R.; Patel, Rupa; Nolan, Nathanial S; Liang, Stephen Y.; Durkin, Michael J.

doi:10.1093/ofid/ofab541

Cited by 7 publications

(5 citation statements)

References 7 publications

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“…Though many patients expressed understanding of safe injection practices, gaps in understanding regarding medication and vaccine prophylaxis continued to persist, even after the bridge-to-health program initiation. Many participants had little understanding about HIV pre-exposure prophylaxis, which was described by this group elsewhere ( 24 ). Further, many had little knowledge about their vaccination status for Hepatitis A and Hepatitis B.…”

Section: Resultsmentioning

confidence: 99%

Experiences Using a Multidisciplinary Model for Treating Injection Drug Use Associated Infections: A Qualitative Study

et al. 2022

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BackgroundOver the past two decades, the United States has experienced a dramatic increase in the rate of injection drug use, injection associated infections, and overdose mortality. A hospital-based program for treating opioid use disorder in people who inject drugs presenting with invasive infections was initiated at an academic tertiary care center in 2020. The goal of this program was to improve care outcomes, enhance patient experiences, and facilitate transition from the hospital to longer term addiction care. The purpose of this study was to interview two cohorts of patients, those admitted before vs. after initiation of this program, to understand the program's impact on care from the patient's perspective and explore ways in which the program could be improved.MethodsThirty patients admitted to the hospital with infectious complications of injection drug use were interviewed using a semi-structured format. Interviews were transcribed and coded. Emergent themes were reported. Limited descriptive statistics were reported based on chart review.ResultsThirty interviews were completed; 16 participants were part of the program (admitted after program implementation) while 14 were not participants (admitted prior to implementation). Common themes associated with hospitalization included inadequate pain control, access to medications for opioid use disorder (MOUD), loss of freedom, stigma from healthcare personnel, and benefits of having an interprofessional team. Participants in the program were more likely to report adequate pain control and access to MOUD and many cited benefits from receiving care from an interprofessional team.ConclusionsPatients with opioid use disorder admitted with injection related infections reported improved experiences when receiving care from an interprofessional team focused on their addiction. However, perceived stigma from healthcare personnel and loss of freedom related to hospitalization were continued barriers to care before and after implementation of this program.

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Section: Resultsmentioning

confidence: 99%

Experiences Using a Multidisciplinary Model for Treating Injection Drug Use Associated Infections: A Qualitative Study

et al. 2022

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“…16 An unintended consequence of education targeted at those with sexual risk factors may be the misperception that injection drug use carries a lower risk of HIV acquisition or that PrEP is exclusive to MSM, according to interviews among PWID on self-perceived risk. 17,18 Stigma against both substance use and sexual identity can result in media and medical silence surrounding the use of PrEP for PWID. 19 Similarly, experienced or anticipated stigma toward PWID from healthcare workers, particularly as it pertains to PrEP adherence, operates as a barrier to PrEP uptake.…”

Section: Discussionmentioning

confidence: 99%

Human immunodeficiency virus pre-exposure prophylaxis awareness among people who inject drugs in Portland, Oregon

2023

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Background Pre-Exposure Prophylaxis (PrEP) to prevent transmission of human immunodeficiency virus (HIV) among people who inject drugs (PWID) has demonstrated efficacy yet awareness of PrEP among PWID is low. Methods 2018 National Behavioral Health Survey data from the Portland, Oregon metropolitan statistical area was analyzed with chi-squared tests and generalized linear models to determine correlates of PrEP awareness among PWID. Results 80% of the sample had at least one indication for PrEP and 15% of the sample was aware of PrEP. Factors associated with higher PrEP awareness were: higher education level (PR = 1.083, CI = 1.018–1.153, p = .012), reporting transactional sex (PR = 1.154, CI = 1.019–1.307, p = .024), and men who have sex with men reporting condomless sex (PR = 1.376, CI = 1.081–1.752, p = .010). Lack of a usual source of care (PR = 0.884, CI = 0.824–0.949, p < .001) was negatively associated with PrEP awareness. Conclusions Interventions to increase PrEP awareness need to target groups with particularly low awareness and be delivered in settings accessible to PWID.

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“…2 It is not uncommon for PWID to feel their risk of HIV is low because they engaged in safe sex practices. 30 This result indicates the need for effective culturally responsive strategies to communicate the risk of contracting and transmitting HIV for PWID.…”

Section: Discussionmentioning

confidence: 99%

Barriers to the uptake of oral pre-exposure prophylaxis among young key populations in Nigeria

Olakunde,

Ujam,

Ndukwe

et al. 2023

Int J STD AIDS

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Background Young key populations (YKP) contribute to the burden of HIV in Nigeria and are a priority population for oral pre-exposure prophylaxis (PrEP). However, their uptake of PrEP remains low. We assessed the main barriers to PrEP uptake and the variation among YKP (15–24 years) in Nigeria. Methods This study was a secondary data analysis of the 2020 Integrated Biological & Behavioural Surveillance Survey conducted among key populations (KP), including female sex workers (FSW), men who have sex with men (MSM), people who inject drugs (PWID), and transgender people (TG), in 12 states in Nigeria. A closed-ended question asking the main reason for not taking PrEP among KP who had never taken PrEP was included in the surveillance questionnaire. We collapsed the responses into six barrier themes. Using multinomial logistic regression analysis, we examined the association between the barriers (dependent variable) and KP group (independent variable), controlling for age, educational attainment, religion, marital status, employment status, and geopolitical zone. Results A total of 1776 YKP were included in this study. The most cited barriers by KP group were: lack of access (28.3%) and fear of side effects (28.3%) by FSW; lack of interest (37.1%) by MSM; low risk perception (65.5%) by PWID; and lack of access (34.4%) by TG. The odds of reporting fear of side effects, lack of access, lack of interest, and nonspecific/others reasons were significantly different by KP group. Conclusions The barriers limiting the uptake of PrEP among YKP vary by KP group. Our results highlight the need for KP-specific interventions to improve the uptake of PrEP among YKP in Nigeria.

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Low Knowledge of HIV PrEP Within a Midwestern US Cohort of Persons who Inject Drugs

Cited by 7 publications

References 7 publications

Experiences Using a Multidisciplinary Model for Treating Injection Drug Use Associated Infections: A Qualitative Study

Experiences Using a Multidisciplinary Model for Treating Injection Drug Use Associated Infections: A Qualitative Study

Human immunodeficiency virus pre-exposure prophylaxis awareness among people who inject drugs in Portland, Oregon

Barriers to the uptake of oral pre-exposure prophylaxis among young key populations in Nigeria

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