Low-level laser therapy in the management of diabetic sensorimotor polyneuropathy

Suganthirababu, Prathap; Sowjanya, B.V. Sai; Prathap, Lavanya; Kumaresan, A.; Jannu, Chiranjeevi; Chandupatla, Vahini Devi

doi:10.5958/0976-5506.2018.01823.5

Cited by 2 publications

(2 citation statements)

References 7 publications

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“…However, its therapeutic effect was not sustained after the 3-month follow-up. Although previous studies (16,19,34) demonstrated that laser intervention alone was able to improve pain or neuropathy symptoms in individuals with type 2 diabetes after several intervention sessions, none of them conducted a long-term follow-up after the end of laser application, and the results were limited to the immediate evaluation of these parameters after the completion of the laser application sessions, which aligns with the present study. The potential physiological effects of LLLT, such as creating a biostimulation effect on the nervous system, lead to the stimulation of intracellular mitochondria, resulting in the production of adenosine triphosphate (ATP) and growth factors.…”

Section: Discussionsupporting

confidence: 84%

“…The laser has the potential to biostimulate the nervous system (13,14), along with other mechanisms such as increasing adenosine triphosphate, releasing endorphins, and exerting anti-inflammatory effects (14,15). Some researchers have proposed LLLT as a novel treatment approach for diabetic individuals experiencing DPN symptoms, advocating for its inclusion in the peripheral nerve rehabilitation protocol for DPN patients (16)(17)(18).…”

Section: Introductionmentioning

confidence: 99%

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Comparison of Tecar Therapy and Low-Level Laser Therapy Separately and Simultaneously on Clinical Symptoms and Health-Related Quality of Life in Individuals with Type 2 Diabetes: A 3-Month Follow-up Study

Javan Amoli,

Khademi Kalantari,

Ahmadpour Emshi

et al. 2024

Int J Endocrinol Metab

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Background: Distal peripheral neuropathy (DPN) is a prevalent issue among patients with type 2 diabetes mellitus. Despite the widespread use of low-level laser therapy (LLLT) and limited use of Tecar therapy in physiotherapy for diabetics, the synergistic effect of these two interventions in a long-term follow-up has not yet been determined. Objectives: This study aimed to compare the effects of Tecar therapy and LLLT separately and simultaneously over a 3-month follow-up period on clinical symptoms and health-related quality of life in individuals with type 2 diabetes and DPN. Methods: In this double-blind, randomized clinical trial, forty-five individuals with type 2 diabetes (30 women and 15 men) with DPN were randomly assigned to three groups of 15 people: Tecar-on + laser-sham, Tecar-on + laser-on, and laser-on + Tecar-sham. The patients received ten treatment sessions and were followed up for 3-months after the last session. Health-related quality of life was assessed using the WHOQOL-BREF Questionnaire, while clinical symptoms, including pain (measured with a Visual Analog Scale), functional balance (evaluated with the timed-up and go test), and neuropathy symptoms (assessed with the Michigan Questionnaire) were also recorded. Results: Inter-group comparison after ten sessions revealed that the Tecar-on + laser-sham and Tecar-on + laser-on groups exhibited significant improvement in neuropathy symptoms compared to the laser-on + Tecar-sham group. Even after the 3-month follow-up, these two groups showed lasting improvement in all variables compared to the laser-on + Tecar-sham group (P < 0.05). The Tecar-on + laser-on group demonstrated a more enduring significant effect on pain scores (P = 0.035) compared to the Tecar-on + laser-sham group after the 3-month follow-up. In intra-group comparison, all three groups showed significant improvement in clinical symptoms and health-related quality of life after ten treatment sessions compared to before treatment (P < 0.05). Moreover, after the 3-month follow-up, both the Tecar-on + laser-sham group and the Tecar-on + laser-on group demonstrated a more lasting significant effect in all variables compared to before treatment (P < 0.05). For the laser-on + Tecar-sham group, a more durable improvement in health-related quality of life (P = 0.000) and neuropathy symptoms (P = 0.011) was reported after the 3-month follow-up compared to before treatment. Conclusions: Although all three groups exhibited significant improvement in clinical symptoms and health-related quality of life in individuals with type 2 diabetes and DPN after ten treatment sessions, the synergistic use of Tecar therapy and LLLT after a long-term follow-up period could lead to more durable therapeutic effects in improving these outcomes for individuals with diabetes.

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Section: Discussionsupporting

confidence: 84%

Section: Introductionmentioning

confidence: 99%

Comparison of Tecar Therapy and Low-Level Laser Therapy Separately and Simultaneously on Clinical Symptoms and Health-Related Quality of Life in Individuals with Type 2 Diabetes: A 3-Month Follow-up Study

Javan Amoli,

Khademi Kalantari,

Ahmadpour Emshi

et al. 2024

Int J Endocrinol Metab

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Action of Ultrasound Therapy in Altering Motor Nerve Conduction Velocity of Ulnar Nerve

Suganthirababu

Alagesan

Prathap

et al. 2019

Biomed. Pharmacol. J.

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Ultrasound therapy is one of the commonest and most popular modality used for tissue healing, pain reduction, tissue extensibility and in inflammation by physiotherapists all around the globe. Various sensitivity tests on peripheral nerves are done with ultrasound therapy, yet conclusions are still skeptical, which makes it inconclusive in progressing the modality further into management of nerve disorders. This study aimed to analyze efficiency of therapeutic ultrasound in influencing ulnar nerve conduction velocity. To Analyze the effect of ultrasound therapy in altering motor nerve conduction velocity of ulnar nerve with two therapeutic frequencies. 40 healthy individuals were included according to the selection criteria and they were explained about safety and simplicity of procedure and informed consent was obtained. All the participants were randomly assigned into two groups as 20 in each group. Group-A was given ultrasound therapy at specific site of elbow to target the ulnar nerve with 1MHz frequency and Group–B followed the same procedure with 3MHz frequency. Pre and Post to ultrasound therapy application Motor Nerve Conduction Velocity (MNCV) of ulnar nerve were recorded for both the groups. The posttest mean of MNCV for forearm segment and arm segment for Group A and Group B showed statistically significant difference (P Value <0.001).The analysis done by the statistical data also revealed that the MNCV at forearm segment showed an increase in velocity compared to its pretest values, whereas the post MNCV values at arm component showed a decrease in velocity when compared to its pretest values. Among comparison the data within the groups it is evident that group A with 1 MHz of ultrasound sonification is more capable of altering the MNCV values in comparison with the 3MHz. frequency. Findings of this study conclude that ultrasound therapy can be used effectively in altering conduction velocity of a nerve and it has a potential ability to facilitate or inhibit a nerve physiological function.

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Low-level laser therapy in the management of diabetic sensorimotor polyneuropathy

Cited by 2 publications

References 7 publications

Comparison of Tecar Therapy and Low-Level Laser Therapy Separately and Simultaneously on Clinical Symptoms and Health-Related Quality of Life in Individuals with Type 2 Diabetes: A 3-Month Follow-up Study

Comparison of Tecar Therapy and Low-Level Laser Therapy Separately and Simultaneously on Clinical Symptoms and Health-Related Quality of Life in Individuals with Type 2 Diabetes: A 3-Month Follow-up Study

Action of Ultrasound Therapy in Altering Motor Nerve Conduction Velocity of Ulnar Nerve

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