Low levels of immunoglobulin A in children with intrinsic asthma: a possible protection against atopy

Timing of Bifidobacterium Administration Influences the Development of Allergy to Ovalbumin in Mice

“…The decreased levels of OVA-specific IgA, IgG1 and IgG2a in the pre-treatment groups are consistent with those of Mandic et al (2004) who reported that the levels of IgG and IgA are high in allergic asthma patients compared to healthy children. Fig.…”

Dose-dependent allergic responses to an extract of Penicillium chrysogenum in BALB/c mice

“…Cats, experimentally exposed to the common allergen Bermuda grass, had antigen-specific BALF IgA levels that were significantly increased after allergen sensitization (Norris et al, 2003). However, as we saw in this mice model, serum IgA levels in asthmatics were not different from controls (Mandic et al, 2004;Najam et al, 1999). Reports on BALF IgA levels in human allergic diseases (Drent et al, 1993;Peebles et al, 1995) support the idea of involvement of IgA in allergic asthma.…”

Lower immunglobulin A levels but not lower cortisol or α-amylase activity in children with chronic tension-type headache

“…On the other hand, it is more plausible that chronic pain tends to induce immunological defences, which is supported by the fact that IgA concentrations were lower in those children with a longer history of headache. Lower IgA concentrations induced by headache would predispose to higher incidence of respiratory illness and asthma (35,36). Future longitudinal studies are required to further elucidate the causal relationship between changes in the immune system and CTTH in children.…”