Abstract-For a family/sequence of Space-Time Block Codes (STBCs) C1, C2, . . . , with increasing number of transmit antennas Ni, with rates Ri complex symbols per channel use (cspcu), i = 1, 2, . . . , the asymptotic normalized rate is defined as limi→∞. A family of STBCs is said to be asymptotically-good if the asymptotic normalized rate is non-zero, i.e., when the rate scales as a non-zero fraction of the number of transmit antennas, and the family of STBCs is said to be asymptotically-optimal if the asymptotic normalized rate is 1, which is the maximum possible value. In this paper, we construct a new class of full-diversity STBCs that have the least maximum-likelihood (ML) decoding complexity among all known codes for any number of transmit antennas N > 1 and rates R > 1 cspcu. For a large set of (R, N ) pairs, the new codes have lower ML decoding complexity than the codes already available in the literature. Among the new codes, the class of full-rate codes (R = N ) are asymptotically-optimal and fast-decodable, and for N > 5 have lower ML decoding complexity than all other families of asymptotically-optimal, fastdecodable, full-diversity STBCs available in the literature. The construction of the new STBCs is facilitated by the following further contributions of this paper: (i) For g > 1, we construct g-group ML-decodable codes with rates greater than one cspcu. These codes are asymptotically-good too. For g > 2, these are the first instances of g-group ML-decodable codes with rates greater than 1 cspcu presented in the literature. (ii) We construct a new class of fast-group-decodable codes (codes that combine the low ML decoding complexity properties of multigroup ML decodable codes and fast-decodable codes) for all even number of transmit antennas and rates 1 < R ≤ 5/4. (iii) Given a design with fullrank linear dispersion matrices, we show that a full-diversity STBC can be constructed from this design by encoding the real symbols independently using only regular PAM constellations 1 .