Low‐molecular‐weight collagen peptides supplement promotes a healthy skin: A randomized, double‐blinded, placebo‐controlled study

Abstract

BackgroundOral collagen peptides supplementation was reported to improve skin integrity and counteract skin aging.AimsA randomized, double‐blinded, placebo‐controlled study was conducted to clinically evaluate the impact of low‐molecular‐weight collagen peptides on the human skin.Patients/MethodsHealthy adult participants (n = 100) were randomly assigned to receive a test product containing low‐molecular‐weight collagen peptides or a placebo. Parameters of skin wrinkles, elasticity, hydration, and whitening (melanin and erythema indexes) were measured at baseline and after 4, 8, and 12 weeks.ResultsCompared with the placebo group, the average skin roughness, maximum of all peak‐to‐valley values, maximum peak height of the wrinkle, and average maximum height of the wrinkle were significantly improved in the test group. Parameters of skin elasticity, including overall elasticity, net elasticity, and biological elasticity, were also significantly improved in the test group at Week 12 as compared with the placebo group. Moreover, skin hydration and whitening parameters changed more significantly in the test group than in the placebo group. None of the participants experienced adverse events related to the test product.ConclusionsTaken together, these findings suggest that low‐molecular‐weight collagen peptides supplementation can safely ehance human skin wrinkling, hydration, elasticity, and whitening properties.

Oral consumption of Bonito fish‐derived elastin peptide (VGPG Elastin®) improves biophysical properties in aging skin: A randomized, double‐blinded, placebo‐controlled study

“…32 Additionally, a previous report in our group observed an 18% dropout rate overall, with 11% in the test group. 33 This study had a few limitations. First, we did not conduct a followup assessment.…”

“… 32 Additionally, a previous report in our group observed an 18% dropout rate overall, with 11% in the test group. 33 …”

Unlocking the Therapeutic Potential of Marine Collagen: A Scientific Exploration for Delaying Skin Aging

“…Hyaluronic acid plays an important role in skin moisture retention [56]. Previous literature on oral collagen supplements has shown evidence of targeting age-related concerns and improving skin integrity [57,58]. Marine collagen and collagen peptides, especially from fish, have demonstrated significant effects on skin hydration.…”

“…Marine collagen and collagen peptides, especially from fish, have demonstrated significant effects on skin hydration. When administered orally, collagen hydrolysates can restore the production of hyaluronic acid to improve skin hydration [57,58]. Other studies have reported that canary seed peptides (CSPs) show promising results for skin aging treatments [59].…”

influence of available oral collagen supplementation on the function of joints and skin

“…This property makes them a promising solution to combat the effects of aging caused by ultraviolet B radiation. 20 One study aimed to evaluate the efficacy and safety of low-molecular-weight collagen peptides. In a randomized, double-blinded trial, multiple skin parameters were analyzed, including the wrinkle height, length and volume, skin hydration, transepidermal water loss, and overall elasticity.After 12 weeks, the measured skin parameters were significantly improved in the test product group compared to the placebo group.…”