Sacha Inchi (Plukenetia volubilis L.) is a plant of the Euphorbiaceae family with a great economic expansion in Central and South America, as well as in some South-East Asiatic countries (Gutiérrez et al., 2019).This promising crop has potential industrial applications in foods, pharmaceuticals, and cosmetics, since their fruits (shell-covered kernels) are a good source of oil (35%-60%) rich in polyunsaturated fatty acids and tocopherols (Gutiérrez et al., 2017). The main fatty acids of Sacha Inchi oil (SIO) are α-linolenic (47%-51%) and linoleic (34%-37%) (Gutiérrez et al., 2011). The most abundant tocopherols in SIO are γ-and δ-tocopherol, ranging from 50 to 114 and from 30 to 125 mg per 100 g, respectively (Gutiérrez et al., 2017). SIO is generally consumed as dressing for salads or as a food supplement. However, to harness the wide range of health benefits of the essential fatty acids, for example, to avoiding cognitive impairment,