Low Potassium Intake: A Common Risk Factor for Nephrolithiasis in Patients with High Blood Pressure

Abate, Veronica; Vergatti, Anita; Fiore, Antonella; Forte, A; Attanasio, A.; Altavilla, Nadia; Filippo, Gianpaolo De; Rendina, Domenico; D’Elia, Lanfranco

doi:10.1007/s40292-023-00587-0

Cited by 3 publications

(2 citation statements)

References 47 publications

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“…Augmenting potassium fertilizer application resulted in higher potassium content in fruits and vegetables (Woldemariam et al, 2018). Consumption of vegetables with higher levels of potassium reduces the incidence of stroke, nephrolithiasis, hypertension, and osteoporosis (Abate et al, 2023). As experimented by Tariq et al, (2018) higher potassium content was crucial for fast fruiting and full yield potential for plants which was achieved by increasing K application.…”

Section: Discussionmentioning

confidence: 98%

RETRACTED: Comparative Analysis of Different Potassium Treatments on the Foliar Nutrient Composition of Hydroponically Grown Eggplant (Solanum melongena) in High-Tech Greenhouse

Shrestha,

Yadav

2023

Preprint

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Potassium is the keystone nutrient in eggplant cultivation, influencing not only plant health but their ability to absorb essential elements for optimal growth and fruit development. However, the exact relationship between potassium and nutrient uptake by eggplants is still unclear. Three varieties Monarch, Lydia, & Lorraine were used to study the impact of varied potassium levels on the nutrient composition of hydroponically grown eggplant inside the high-tech-greenhouse. The result showed Potassium exerted a pronounced influence on nutrient absorption and leaf composition across various eggplant cultivars. Both low and high levels of potassium resulted in poor K content in the leaves of eggplants. Meanwhile, eggplant grown at optimal levels had higher potassium content in the leaves. The P, Cl, & Na content of leaves decreased with the increase in the application of K in the nutrient medium and was significantly different. The correlation coefficient between K content in leaves was − 0.44***, 0.37***, & 0.44*** with Ca, Cl, & Na respectively. These results emphasize the importance of carefully and precisely balancing potassium fertilization due to its complex interplay of synergistic and antagonistic relationships with essential nutrients, impacting their uptake and distribution.

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Section: Discussionmentioning

confidence: 98%

RETRACTED: Comparative Analysis of Different Potassium Treatments on the Foliar Nutrient Composition of Hydroponically Grown Eggplant (Solanum melongena) in High-Tech Greenhouse

Shrestha,

Yadav

2023

Preprint

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“…Citrate is a strong inhibitor of stone formation by decreasing the supersaturation of calcium salt [ 41 ]. Previous studies indicate that citrus and non-citrus fruits are natural sources of dietary citrate, and that their elevated dietary intake significantly increases uCit and uK, thus lowering the NL risk [ 17 , 42 ]. On the other hand, higher salt consumption has been associated with higher uUA, which is involved in the nucleation and crystallization of calcium and/or urate kidney stones [ 43 , 44 , 45 ].…”

Section: Discussionmentioning

confidence: 99%

Adherence to Mediterranean Diet, Dietary Salt Intake, and Susceptibility to Nephrolithiasis: A Case–Control Study

Abate,

Vergatti,

Iaccarino Idelson

et al. 2024

Nutrients

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Unhealthy dietary habits play a key role in the pathogenesis of nephrolithiasis (NL). The aims of this case–control study were to evaluate (i) the adherence to the Mediterranean Diet (MD) and the dietary salt intake in stone-forming patients (SF), (ii) the relationship occurring between MD adherence, salt intake and NL-related metabolic risk factors in SF, and (iii) the impact of combined high MD adherence and low salt intake on NL susceptibility. From 1 January 2018 to 31 December 2019, we recruited all SF consecutively referred to the Extracorporeal Shock Wave Lithotripsy (ESWL) center of Federico II University, and at least two control subjects without a personal history of NL, age-, sex-, and body mass index-matched to SF (NSF). All study participants were interviewed using the validated MEDI-LITE and MINISAL questionnaires. In an SF subgroup, the NL-related metabolic risk factors were also evaluated. SF showed a lower MD adherence and a higher salt intake compared with NSF. The NL susceptibility decreased by 36% [OR: 0.64 (0.59–0.70); p < 0.01] for each point of increase in MEDI-LITE score, while it increased by 13% [OR: 1.13 (1.03–1.25); p = 0.01] for each point of increase in MINISAL score. The SF prevalence was higher among subjects showing combined low MD adherence and high salt intake. In SF, the MEDI-LITE score directly correlated with 24 h-citraturia, whereas the MINISAL score directly correlated with urinary sodium and uric acid excretion. In conclusion, high MD adherence and low salt intake are associated with a reduced NL susceptibility, both separately and in combination.

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Imiglucerase, cholecalciferol, and bone-diet in skeletal health management of type I Gaucher disease patients: a pilot study and systematic review

Barbato,

Vergatti,

Giaquinto

et al. 2024

JBMR Plus

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Introduction The skeletal anomalies represent a characteristic feature of Gaucher disease type 1 (GD1). We evaluated the impact of an integrated therapy with Enzyme Replacement Therapy (ERT), cholecalciferol, and a normocalcemic-normocaloric-hyposodic diet (bone diet) on bone health in GD1 patients. We also performed a systematic review to compare our results with available data. Methods From January 1st,2015 to February 28th, 2019, all GD1 patients referring to Federico II University were enrolled and treated with the integrated therapy. The bone turnover markers (BTMs) and bone mineral density (BMD) were evaluated at baseline (T0) and after 24 months (T24). Results We enrolled 25 GD1 patients, all showing 25OHD levels <50 nmol/l (hypovitaminosis D) at T0. The response to cholecalciferol treatment was effective, showing a direct relationship between 25OHD levels before and after treatment. At T0, 2 GD1 patients showed fragility fractures, 5 the Erlenmeyer flask deformity, 3 osteonecrosis and 7 BMD Z-score ≤ -2. Overall, GD1 patients with bone anomalies showed higher C-terminal telopeptide levels compared to those without bone anomalies. During the 2-years follow-up no new bone anomalies occurred. At T24, the BMD remained stable in the entire study cohort and in patients with bone anomalies. The systematic review showed that our study is the first that evaluated all bone health parameters. Conclusion In GD1 patients, hypovitaminosis D is prevalent. The response to cholecalciferol treatment is effective but different to healthy subjects and to patients with metabolic bone disorders. The integrated therapy including ERT, cholecalciferol, and bone diet guarantee the bone health.

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Low Potassium Intake: A Common Risk Factor for Nephrolithiasis in Patients with High Blood Pressure

Cited by 3 publications

References 47 publications

RETRACTED: Comparative Analysis of Different Potassium Treatments on the Foliar Nutrient Composition of Hydroponically Grown Eggplant (Solanum melongena) in High-Tech Greenhouse

RETRACTED: Comparative Analysis of Different Potassium Treatments on the Foliar Nutrient Composition of Hydroponically Grown Eggplant (Solanum melongena) in High-Tech Greenhouse

Adherence to Mediterranean Diet, Dietary Salt Intake, and Susceptibility to Nephrolithiasis: A Case–Control Study

Imiglucerase, cholecalciferol, and bone-diet in skeletal health management of type I Gaucher disease patients: a pilot study and systematic review

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