This paper presents a high speed design of 4-to-2 compressor, using Carbon Nanotube Field Effect Transistor (CNFET). CNFET is very suitable for low-voltage and high-frequency applications. Several conventional and state-of-the-art 4-to-2 compressor cells are also surveyed and compared in this paper. All designs are simulated by HSPICE with 32 nm CNFET technology. These designs have also been simulated at different supply voltage and different frequencies, load capacitors, and temperatures. The simulation results confirm that the proposed design is the fastest 4-to-2 compressor in different working circumstance.