Low prevalence of HIV and other sexually transmitted infections in young women attending a youth counselling service in Maputo, Mozambique

Melo, Josefa; Folgosa, Elena; Manjate, Delfina; Osman, Nafissa; François, Isabelle; Temmerman, Marleen; Cappuccinelli, Pietro Antonio; Colombo, Mauro

doi:10.1111/j.1365-3156.2007.01972.x

Cited by 12 publications

(19 citation statements)

References 15 publications

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“…The SAAJ clinic provides services (free of charge) for young people seeking counseling and treatment for any health problem, but with particular attention to reproductive health and control of sexually transmitted infections (STIs). A low prevalence of STIs and HIV and a high level of awareness has previously been reported in a study performed at the SAAJ clinic [14].…”

Section: Methodsmentioning

confidence: 65%

Reference Values for Clinical Laboratory Parameters in Young Adults in Maputo, Mozambique

et al. 2014

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BackgroundClinical laboratory reference values from North American and European populations are currently used in most Africans countries due to the absence of locally derived reference ranges, despite previous studies reporting significant differences between populations. Our aim was to define reference ranges for both genders in 18 to 24 year-old Mozambicans in preparation for clinical vaccine trials.MethodsA cross-sectional study including 257 volunteers (102 males and 155 females) between 18 and 24 years was performedat a youth clinic in Maputo, Mozambique. All volunteers were clinically healthy and human immunodeficiency virus, Hepatitis B virus and syphilis negative.Median and 95% reference ranges were calculated for immunological, hematological and chemistry parameters. Ranges were compared with those reported based on populations in other African countries and the US. The impact of applying US NIH Division of AIDS (DAIDS) toxicity tables was assessed.ResultsThe immunology ranges were comparable to those reported for the US and western Kenya.There were significant gender differences in CD4+ T cell values 713 cells/µL in males versus 824 cells/µL in females (p<0.0001). Hematologic values differed from the US values but were similar to reports of populations in western Kenya and Uganda. The lower and upper limits of the ranges for hemoglobin, hematocrit, red blood cells, white blood cells and lymphocytes were somewhat lower than those from these African countries. The chemistry values were comparable to US values, with few exceptions. The upper limits for ALT, AST, bilirubin, cholesterol and triglycerides were higher than those from the US. DAIDStables for adverse events predicted 297 adverse events and 159 (62%) of the volunteers would have been excluded.ConclusionThis study is the first to determine normal laboratory parameters in Mozambique. Our results underscore the necessity of establishing region-specific clinical reference ranges for proper patient management and safe conduct of clinical trials.

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Section: Methodsmentioning

confidence: 65%

Reference Values for Clinical Laboratory Parameters in Young Adults in Maputo, Mozambique

et al. 2014

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“…A review in 80 developing countries found that youth-friendly services increased young people's use of health services [41]. Interventions in two countries, Mozambique and Madagascar, show that services that include confidential, non-judgemental, convenient and affordable HIV testing and counselling and family planning information and services can increase use of services by youth [42,43]. …”

Section: Reviewmentioning

confidence: 99%

What works to meet the sexual and reproductive health needs of women living with HIV/AIDS

Hardee

Croce-Galis

Hall

2011

Journal of the International AIDS Society

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It is critical to include a sexual and reproductive health lens in HIV programming as most HIV transmission occurs through sexual intercourse. As global attention is focusing on the sexual and reproductive health needs of women living with HIV, identifying which interventions work becomes vitally important. What evidence exists to support sexual and reproductive health programming related to HIV programmes?This article reviews the evidence of what works to meet the sexual and reproductive health needs of women living with HIV in developing countries and includes 35 studies and evaluations of eight general interventions using various methods of implementation science from 15 countries. Data are primarily from 2000-2009. Searches to identify effective evaluations used SCOPUS, Popline, Medline, websites and consultations with experts. Evidence was ranked using the Gray Scale.A range of successful and promising interventions to improve the sexual and reproductive health and rights of women living with HIV include: providing contraceptives and family planning counselling as part of HIV services; ensuring early postpartum visits providing family planning and HIV information and services; providing youth-friendly services; supporting information and skills building; supporting disclosure; providing cervical cancer screening; and promoting condom use for dual protection against pregnancy and HIV. Provision of antiretrovirals can also increase protective behaviours, including condom use.While many gaps in programming and research remain, much can be done now to operationalize evidence-based effective interventions to meet the sexual and reproductive health needs of women living with HIV.

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“…A correct diagnosis of a STI is essentials for proper and effective treatment. The concern in the diagnosis and treatment of STIs is not due to the fact that they are infections caused by pathological agents, but also in their possible correlation with increased transition and acquisition of Human Immunodeficiency Virus (HIV) infection [10][11][12].…”

Section: Introductionmentioning

confidence: 99%

“…Information on the prevalence of other sexually transmitted infections in pregnant women in Mozambique is scarce and it is known that these infections during pregnancy can have drastic consequences for pregnancy and for the newborn; they are associated with considerable discomfort and may result in termination of pregnancy, low birth weight and increased infant mortality [33]. Although these infections affect men and women, in developing countries such as Mozambique the situation is very complicated for women for several reasons: women are less able to seek treatment in relation to men, in certain population groups there are social consequences such as stigmatization when women are infertile, including the partner`s right to divorce [11,34]. On the other hand, in these countries complications related to STIs are the major causes of mortality and morbidity of the mother and child during pregnancy [11].…”

Section: Introductionmentioning

confidence: 99%

Intellectual Corruption in Modern Science: A Case Study

2019

JCRC

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Sexually transmitted infections are among the most common public health problems worldwide. Female and male infertility, mother to child transmission, causing miscarriages or congenital disease, and increased risk for Human Immunodeficiency Virus infection (HIV) are some of their consequences. In Sub-Saharan Africa countries, such as Mozambique, the prevalence of these infections is high, women being those who carry the higher burden. Thus we developed this cross-sectional study with objective of characterizing some sexually transmitted infections, HIV infection, syphilis and trichomoniasis in pregnant women, verifying if their management was in accordance with guidelines and recommendations in the country and identifying practice, Knowledge and associated risk factors. Samples were collected from 253 pregnant women attending Centro de Saúde de Maxixe. Vaginal samples were obtained and observed microscopically by wet mount and direct microscopic examination (Trichomonas vaginalis). HIV antibody testing was performed with the tests Determine HIV-1/2 and Uni-GoldTM and against, T. pallidum by RPR, SD BIOLINE Syphilis 3.0 and Determine TP tests in plasma samples. In this study, 11.1% of the pregnant women were infected with HIV, 2.8% with active syphilis, 5.1% with Trichomonas vaginalis and 9.1% with yeast. Antibodies against T. pallidum were identified in 8,3% of these women. In relation to HIV, 7, 5% of them were new cases. Samples were taken from 253 pregnant women attending ante-natal outpatient consultation at the health centre, which were informed about the nature of the study and submitted to a semi-structured interview after signing the free informed consent. In this study, the inconsistency on condoms use and the existence of multiple partners by the participants contributing for these infections transmission. Participants have shown that they had information about these infections modes of transmission, as also which measures to use to prevent them. A significant number of women present with any symptom related to infections that were diagnosed to them, proving that the use of syndrome approach in vaginal discharge must be given some thought in relation to its value in this situation. The data obtained in this study shows that some gaps also exist in the prenatal care clinics of this Centre, from routine procedures that are not performed in accordance with MISAU recommendations. The high prevalence of some STI found in this population, their risk behavior, together with the non-observance of some guidelines in the management of those infections by the health personal very worrying. The implementation of a teaching program on quality control, prevention and management of these infections by the health professional seems to us to be of utmost importance, so these can act in accordance with the present guidelines and transmit correct information to the pregnant women who attend prenatal care.

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Low prevalence of HIV and other sexually transmitted infections in young women attending a youth counselling service in Maputo, Mozambique

Abstract: The low prevalence of STI and HIV may be related in part to the high level of awareness registered in the group.

Cited by 12 publications

References 15 publications

Reference Values for Clinical Laboratory Parameters in Young Adults in Maputo, Mozambique

Reference Values for Clinical Laboratory Parameters in Young Adults in Maputo, Mozambique

What works to meet the sexual and reproductive health needs of women living with HIV/AIDS

Intellectual Corruption in Modern Science: A Case Study

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