Low radiation dose multislice CT colonography in children: Experience after 100 studies

Capuñay, Carlos; Carrascosa, Patrícia; Bou-Khair, Adriana; Castagnino, Norma; Ninomiya, Inés; Carrascosa, Jorge

doi:10.1016/j.ejrad.2005.06.002

Cited by 15 publications

(12 citation statements)

References 8 publications

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“…Several investigators have demonstrated that CTC is an accurate and reproducible method for detecting colonic polyps lager than 5 mm in diameter in adults [9]. Capuñay et al performed CTC in 100 children with rectal bleeding; they found sensitivity and specificity of 100 and 96%, respectively, for the detection polyps larger than 9 mm, 90 and 90% for polyps 5-9 mm, and 81 and 90% for lesions smaller than 5 mm [2]. Conventional colonoscopy and barium enema X-rays are generally accepted for colorectal screening in children.…”

Section: Discussionmentioning

confidence: 97%

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Colorectal screening with single scan CT colonography in children

et al. 2007

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The purpose of this study was to evaluate the feasibility of single scan CT colonography (CTC) using polyethylene glycol electrolyte solution with contrast medium (PEG-C) bowel preparation in children. Seven patients suspected of colorectal elevated lesions were subjected to CTC. All patients underwent bowel preparation using polyethylene glycol electrolyte solution (PEG) at a dose of 32 +/- 3 ml/kgBW before the day of CTC. The water-soluble contrast agent was given to the patients at a dose of 0.6 +/- 0.1 ml/kgBW the next morning. After colonic air insufflation, the patient was scanned axially with a single run. After evaluation of multiplanar reformation images, 3-dimensional images (CT enema and virtual endoscopy image) were reconstructed. CT enema image was composed from air image and contrast-medium image. All studies were performed without complications. CTC showed the entire colon without blind spots in all patients with only single scan. In conclusion, the single scan CTC using PEG-C preparation is safe and less invasive compared to conventional CTC due to the shorter examination time and lower radiation dose.

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Section: Discussionmentioning

confidence: 97%

“…There are few reports related to the technique in children [1,2]. CTC requires bowel preparation and colonic insufflation.…”

Section: Introductionmentioning

confidence: 98%

Colorectal screening with single scan CT colonography in children

et al. 2007

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“…In 2006 the American College of Radiology recommended use of low-dose protocols for screening CT colonography [3]. Previous feasibility studies on CTC performed at low radiation doses showed moderate to good detection of medium and large polyps [4][5][6][7][8][9][10][11][12]. Only two of these studies [5,7] used primary three-dimensional (3D) readings to interpret lowdose CTC examinations.…”

Section: Introductionmentioning

confidence: 99%

Evaluation of image quality and lesion perception by human readers on 3D CT colonography: comparison of standard and low radiation dose

et al. 2009

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“…Because of these competing issues, this area in general is controversial and further study is expected [60,61]. Lower-dose CT colonography appears to be readily feasible [49,50,62] and does not appear to affect the accuracy of the test. This is an active area for future investigation; it is expected that radiation doses will become lower and lower in the future.…”

Section: New Technologymentioning

confidence: 99%

Computed Tomographic and Magnetic Resonance Colonography: Challenge for Colonoscopy

Rockey

2012

Dig Dis

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Background: Computed tomographic (CT) and magnetic resonance (MR) colonography are new noninvasive techniques to examine the colon. Methods: A literature search was performed through 2/1/2012, and relevant studies included in the review. Results: MR colonography is evolving, and holds the promise that it may achieve high-level sensitivity for adenomas and cancers without exposure to radiation. CT colonography is much more mature at this point in time, and has received great attention in the last decade as a colon imaging tool, including potentially as a primary colon cancer screening method. Its accuracy for detection of polypoid lesions ≥1 cm is high, likely close to that of colonoscopy. New techniques focusing on minimally prepped CT colonography hold the potential of making the procedure more widely accepted. While radiation exposure with CT colonography is a concern, this risk is likely very modest, particularly if used in patients over the age of 50. CT colonography, while a viable colon cancer screening modality in the USA, could not be widely implemented, largely because of lack of standards for training and reading, and because the number of skilled readers is limited. Summary: MR and CT colonography are relatively novel and exciting modalities that can be used to identify colonic lesions. They promise a high level of sensitivity and pose essentially no (MR) or modest (CT) risks. Future investigation will likely lead to wider acceptance of both of these tests, including perhaps to their use in colon cancer screening programs.

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Low radiation dose multislice CT colonography in children: Experience after 100 studies

Cited by 15 publications

References 8 publications

Colorectal screening with single scan CT colonography in children

Colorectal screening with single scan CT colonography in children

Evaluation of image quality and lesion perception by human readers on 3D CT colonography: comparison of standard and low radiation dose

Computed Tomographic and Magnetic Resonance Colonography: Challenge for Colonoscopy

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