“…2,4,5,25,[36][37][38] The significant blood loss and transfusions may be related to several factors, such as the relatively advanced age of many patients with ASD, their high rate of associated comorbidities, as well as surgically related factors (i.e., posterior approach, pelvic fixation, osteotomy, and longer operative duration). 26,42 The need for blood transfusions to compensate for these losses is associated with perioperative complications such as infections, thromboembolic events, and hemolytic transfusion reactions. 8,12,13,19,20,33,34,39,41,46 Also, patients requiring blood transfusion have been shown to have prolonged hospitalization, increased readmission and reoperation rates, and higher surgery-related costs.…”