2005
DOI: 10.1128/aac.49.10.4404-4405.2005
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Low Rates of Cutaneous Adverse Reactions to Alcohol-Based Hand Hygiene Solution during Prolonged Use in a Large Teaching Hospital

Abstract: We assessed cutaneous adverse reactions (CARs) to alcohol-based hand rub (ABHR) after the introduction of a hand hygiene culture change program at our institution. CARs were infrequent among exposed health care workers (HCWs) (13/2,750; 0.47%; 1 CAR per 72 years of HCW exposure) and were not influenced by the duration or intensity of ABHR use but were associated with the presence of irritant contact dermatitis.

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Cited by 52 publications
(40 citation statements)
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“…In one study, 2750 health care workers were evaluated for the incidence of CARs and 13 (0.47%) reported such an event. 26 There were zero non-CARs. Irritant contact dermatitis was found in all 13 participants, of whom 9 had previous skin problems (dermatitis/eczema or adverse reactions to various skin products).…”
Section: Side Effectsmentioning
confidence: 97%
“…In one study, 2750 health care workers were evaluated for the incidence of CARs and 13 (0.47%) reported such an event. 26 There were zero non-CARs. Irritant contact dermatitis was found in all 13 participants, of whom 9 had previous skin problems (dermatitis/eczema or adverse reactions to various skin products).…”
Section: Side Effectsmentioning
confidence: 97%
“…585 Graham and colleagues reported low rates of cutaneous adverse reactions to an alcohol-based handrub (isopropyl alcohol 70%) formulation containing chlorhexidine (0.5%) with emollient. 548 Information regarding the irritancy potential of commercially prepared hand hygiene products, which is often determined by measuring the transepidermal water loss of persons using the preparation, may be available from the manufacturer. Other factors that may contribute to dermatitis associated with frequent hand cleansing include using hot water for handwashing, low relative humidity (most common in winter months in the northern hemisphere), failure to use supplementary hand lotion or cream, and perhaps the quality of paper towels.…”
Section: Frequency and Pathophysiology Of Irritant Contact Dermatitismentioning
confidence: 99%
“…197 Overall, skin dermatitis is more frequently associated with hand antisepsis using a medicated soap than with an alcohol-based handrub. 548 Boyce and colleagues quantified the epidermal water content of the dorsal surface of nurses' hands by measuring electrical capacitance of the skin. The water content decreased significantly during the washing phase compared with the alcohol-based handrub-in phase.…”
Section: Side-effects Of Surgical Hand Scrubmentioning
confidence: 99%
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